揿针联合酪酸梭菌肠球菌三联活菌片治疗气滞型功能性便秘患者的效果  

Effects of press needle combined with Clostridium butyricum enterococcus triple viable tablets in treatment of patients with functional constipation of qi stagnation type

作　　者：郭满 GUO Man(Anorectal Department of Nanyang Hospital of Traditional Chinese Medicine,Nanyang 473000 Henan,China)

机构地区：[1]南阳市中医院肛肠科,河南南阳473000

出　　处：《中国民康医学》2025年第5期104-106,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察揿针联合酪酸梭菌肠球菌三联活菌片治疗气滞型功能性便秘患者的效果。方法:选取2022年1月至2023年5月该院收治的92例气滞型功能性便秘患者进行前瞻性研究,按照随机数字表法分为研究组与对照组各46例。对照组采用酪酸梭菌肠球菌三联活菌片治疗,研究组在对照组基础上联合揿针治疗,比较两组排便次数和排便性状开始改善时间、血清胃肠激素(促胃液素、促胃动素和生长抑素)水平、血清肠神经递质(P物质、一氧化氮)水平、肠道菌群(酵母菌、肠杆菌、乳杆菌和双歧杆菌)水平以及不良反应发生率。结果:研究组排便次数、排便性状开始改善时间短于对照组,差异均有统计学意义(P<0.05);治疗后,研究组促胃液素、促胃动素、P物质、乳杆菌、双歧杆菌水平高于对照组,生长抑素、一氧化氮、酵母菌、肠杆菌水平低于对照组,差异均有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:揿针联合酪酸梭菌肠球菌三联活菌片治疗气滞型功能性便秘患者可缩短排便次数、排便性状开始改善时间,以及改善血清胃肠激素、血清肠神经递质和肠道菌群水平,效果优于单纯酪酸梭菌肠球菌三联活菌片治疗。Objective:To observe effects of press needle combined with Clostridium butyricum enterococcus triple viable tablets in treatment of patients with functional constipation of qi stagnation type.Methods:A prospective study was conducted on 92 patients with functional constipation of qi stagnation type admitted to the hospital from January 2022 to May 2023.According to the random number table method,they were divided into study group and control group,46 cases in each group.The control group was treated with Clostridium butyricum enterococcus triple viable tablets,while the study group was treated with press needle on the basis of that of the control group.The defecation frequency,the defecation improvement time,the levels of serum gastrointestinal hormones(gastrin,motilin and somatostatin),the levels of serum intestinal neurotransmitters(substance P and nitric oxide),the levels of intestinal flora(Saccharomycetes,Enterobacter,Lactobacillus and Bifidobacterium),and the incidence of adverse reactions were compared between the two groups.Results:The defecation frequency and the defecation character improvement time in the study group was shorter than that in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of gastrin,motilin,substance P,Lactobacillus and Bifidobacterium in the study group were higher than those in the control group,the levels of somatostatin,nitric oxide,Saccharomycetes and Enterobacter in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Press needle combined with Clostridium butyricum enterococcus triple viable tablets in the treatment of the patients with functional constipation of qi stagnation type can shorten the defecation frequency,the defecation improvement time,and improve the serum gastrointestinal hormone levels,the serum intestinal neurotrans

关 键 词：揿针 酪酸梭菌肠球菌三联活菌片 气滞型 功能性便秘 胃肠激素 肠神经递质 肠道菌群 不良反应 

分 类 号：R442.2[医药卫生—诊断学]