血清MP-IgM、MP-IgG、CRP、D-D水平与肺炎支原体肺炎患儿病情严重程度的相关性  

Correlation between serum MP-IgM,MP-IgG,CRP,D-D levels and severity of disease in children with mycoplasma pneumoniae pneumonia

作　　者：陈嘉莹 胡丽婷 刘凤芝 CHEN Jiaying;HU Liting;LIU Fengzhi(Department of Clinical Laboratory of Shunde Women and Children’s Hospital of Guangdong Medical University,Foshan Shunde Maternal and Child Health Hospital,Foshan 528300 Guangdong,China)

机构地区：[1]广东医科大学顺德妇女儿童医院佛山市顺德区妇幼保健院检验科,广东佛山528300

出　　处：《中国民康医学》2025年第5期136-138,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:分析血清肺炎支原体IgM抗体(MP-IgM)、肺炎支原体IgG抗体(MP-IgG)、C反应蛋白(CRP)、D-二聚体(D-D水平)与肺炎支原体肺炎(MPP)患儿病情严重程度的相关性。方法:选取2023年1月至2024年6月该院收治的100例MPP患儿为研究对象,设为观察组,同时选取同期100名门诊体检健康儿童作为对照组。比较两组及不同病情严重程度MPP患儿MP-IgM、MP-IgG、CRP、D-D水平,采用Pearson相关性分析对血清MP-IgM、MP-IgG、CRP、D-D水平与MPP患儿病情严重程度的相关性进行分析。结果:观察组血清MP-IgM、MP-IgG、CRP、D-D水平均高于对照组,差异有统计学意义(P<0.05);重症MPP患儿血清MP-IgM、MP-IgG、CRP、D-D水平均高于轻症MPP患儿,差异有统计学意义(P<0.05);Pearson相关性分析结果显示,血清MP-IgM、MP-IgG、CRP、D-D水平与MPP患儿病情严重程度均呈正相关(r>0,P<0.05)。结论:血清MP-IgM、MP-IgG、CRP、D-D水平与MPP患儿病情严重程度均呈正相关。Objective:To analyze correlation between levels of serum Mycoplasma pneumoniae IgM antibody(MP-IgM),Mycoplasma pneumoniae IgG antibody(MP-IgG),C-reactive protein(CRP),D-dimer(D-D) and severity of disease in children with mycoplasma pneumoniae pneumonia(MPP).Methods:A total of 100 children with MPP admitted to this hospital from January 2023 to June 2024 were selected as the observation group,and 100 healthy children in the same period were selected as the control group.The levels of MP-IgM,MP-IgG,CRP and D-D in the two groups and the MPP children with different severity were compared.Pearson correlation analysis was used to analyze the correlation between the serum MP-IgM,MP-IgG,CRP,D-D levels and the severity of MPP in these children.Results:The levels of serum MP-IgM,MP-IgG,CRP and D-D in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of serum MP-IgM,MP-IgG,CRP and D-D in the children with severe MPP were higher than those in the children with mild MPP,and the differences were statistically significant(P<0.05).Pearson correlation analysis showed that the serum MP-IgM,MP-IgG,CRP and D-D levels were positively correlated with the severity of MPP in the children(r>0,P<0.05).Conclusions:The serum MP-IgM,MP-IgG,CRP and D-D levels are positively correlated with the severity of MPP in the children.

关 键 词：肺炎支原体肺炎 肺炎支原体IgG抗体 肺炎支原体IGM抗体 C反应蛋白 D-二聚体 病情严重程度 相关性 

分 类 号：R725.6[医药卫生—儿科]