改良内镜鼻窦手术与传统内镜鼻窦手术治疗慢性鼻窦炎伴鼻息肉患者的效果比较  

Comparison of effects of modified endoscopic sinus surgery and traditional endoscopic sinus surgery in treatment of patients with chronic sinusitis with nasal polyps

作　　者：牛全章 NIU Quanzhang(Department of Otorhinolaryngology of the Fourth People’s Hospital of Xinyang City,Xinyang 464100 Henan,China)

机构地区：[1]信阳市第四人民医院耳鼻咽喉科,河南信阳464100

出　　处：《中国民康医学》2025年第5期146-148,155,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:比较改良内镜鼻窦手术(ESS)与传统ESS治疗慢性鼻窦炎伴鼻息肉(CRSwNP)患者的效果。方法:回顾性分析2021年5月至2024年1月该院收治的84例CRSwNP患者的临床资料,按照手术方案不同将其分为对照组与观察组各42例。对照组采用传统ESS治疗,观察组采用改良ESS治疗。比较两组手术前后临床症状积分(流鼻涕、头痛、鼻塞、水肿)、病情程度(Lund-Kennedy鼻内镜评分系统)评分、生命质量[鼻腔鼻窦结局测试-20量表(SNOT-20)]评分、炎性因子[γ干扰素(IFN-γ)、白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)]水平,以及并发症发生率。结果:术后1个月,两组流鼻涕、头痛、鼻塞、水肿等临床症状积分均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05);术后1个月,两组Lund-Kennedy、SNOT-20评分均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05);术后1 d,两组IFN-γ、IL-1β、TNF-α水平均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为2.38%(1/42),低于对照组的19.05%(8/42),差异有统计学意义(P<0.05)。结论:改良ESS治疗CRSwNP患者可降低临床症状积分、Lund-Kennedy评分、SNOT-20评分、炎性因子水平和并发症发生率,效果优于传统ESS治疗。Objective:To compare effects of modified endoscopic sinus surgery(ESS) and traditional ESS in treatment of patients with chronic rhinosinusitis with nasal polyps(CRSwNP).Methods:The clinical data of 84 patients with CRSwNP admitted to the hospital from May 2021 to January 2024 were retrospectively analyzed.According to different surgical schemes,they were divided into control group and observation group,42 cases in each group.The control group was treated with traditional ESS,while the observation group was treated with modified ESS.The clinical symptom scores(runny nose,headache,nasal congestion,edema),the disease severity(Lund-Kennedy endoscopic scoring system) score,the quality of life [sinonasal outcome test-20(SNOT-20)] score,the inflammatory factors [interferon-γ(IFN-γ),interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α)] levels before and after surgery,and the incidence of complications were compared between the two groups.Results:One month after the surgery,the scores of clinical symptoms such as runny nose,headache,nasal congestion and edema in the two groups were lower than those before the surgery,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).One month after the surgery,the scores of Lund-Kennedy and SNOT-20 in the two groups were lower than those before the surgery,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).One day after the surgery,the levels of IFN-γ,IL-1β and TNF-α in the two groups were higher than those before the surgery,but those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the incidence of complications in the observation group was 2.38%(1/42),which was lower than 19.05%(8/42) in the control group,and the difference was statistically significant(P<0.05).Conclusions:Modified ESS in the treatment of the CRSwNP patients can

关 键 词：改良内镜鼻窦手术 传统内镜鼻窦手术 慢性鼻窦炎伴鼻息肉 病情程度 生命质量 炎性因子 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]