衰弱老年人多重用药管理的证据总结  

Evidence summary for the management of polypharmacy in frail older adults

作　　者：初紫晶[1] 赵晓霜[2] 萨日娜 王雨[4] 王海凤[5] 郭倩倩 李圆圆 赵秋月[7] 赵双双 李虹彦[2] CHU Zijing;ZHAO Xiaoshuang;SA Rina;WANG Yu;WANG Haifeng;GUO Qianqian;LI Yuanyuan;ZHAO Qiuyue;ZHAO Shuangshuang;LI Hongyan(Department of Hepatobiliary and Pancreatic Medicine,The First Hospital of Jilin University,Changchun,130021,China)

机构地区：[1]吉林大学第一医院肝胆胰内科,长春市130021 [2]吉林大学第一医院护理部,长春市130021 [3]吉林大学第一医院眼科,长春市130021 [4]吉林大学第一医院第一手术室,长春市130021 [5]吉林大学第一医院泌尿外一科,长春市130021 [6]吉林大学护理学院,长春市130021 [7]吉林大学第一医院肝胆胰外二科,长春市130021 [8]吉林大学第一医院卒中中心,长春市130021

出　　处：《中国护理管理》2025年第2期236-242,共7页Chinese Nursing Management

基　　金：吉林大学第一医院2024年循证护理专项课题项目(JDYY-XZHL202405);吉林省医疗卫生人才专项(JLSWSRCZX2023-1)。

摘　　要：目的:总结衰弱老年人多重用药管理的相关证据,以期为相关人员药物管理提供依据。方法:系统检索国内外专业网站和数据库中关于衰弱老年人多重用药管理的相关证据,检索时限为建库至2024年2月29日。研究员进行文献质量评价,对符合质量标准的文献进行证据提取和总结。结果:共纳入16篇文献,其中临床决策1篇、指南4篇、专家共识4篇、系统评价4篇、随机对照试验2篇、队列研究1篇。总结出20条关于衰弱老年人多重用药管理的证据,包括风险评估、用药策略调整、个性化干预、精准服药、支持与随访、教育及培训6个方面。结论:本研究汇总的证据可为医护人员、养老护理员和家庭照护者管理衰弱老年人的多重用药情况提供循证依据,可从以上6个方面结合衰弱老年人的意愿和具体的临床情境运用证据,改善衰弱老年人多重用药的问题。Objective:To summarize the evidence on management of polypharmacy in frail older adults,in order to provide a basis for scientific medication management.Methods:We systematically searched relevant evidence on polypharmacy management in frail elderly in professional websites and databases at home and abroad from the database's inception to February 29,2024.Researchers independently evaluated the quality of the literature,extracted and summarized the evidence that met the quality standards.Results:Totally 16 articles were included,including 1 clinical decision-making,4 guidelines,4 expert consensus,4 systematic reviews,2 randomized controlled trials,and 1 cohort study.Totally 20 pieces of evidence were summarized on the polypharmacy management of frail older adults from 6 aspects:risk assessment,medication adjustment strategy,individualized intervention,precision medicine,supporting and follow-up,and education and training.Conclusion:The evidence from this study can provide evidence-based evidence for medical staff,nursing staff,and family caregivers to manage multiple drug use in frail older adults.Medical staff can combine the wishes of the frail elderly and the specific clinical situation from the six aspects above and use the evidence to improve the problem of polypharmacy in frail older adults.

关 键 词：衰弱老年人 多重用药 用药管理 证据总结 

分 类 号：R47[医药卫生—护理学] R197[医药卫生—临床医学]