免疫细胞在狼疮性肾炎发病机制中的研究进展  

Research progress of immune cells in pathogenesis of lupus nephritis

作　　者：代双宇 曲书强[1] 陈汉宸 郑玉玲 Dai Shuangyu;Qu Shuqiang;Chen Hanchen;Zheng Yuling(Pediatrics Department,the Second Affiliated Hospital of Harbin Medical University,Harbin 150081,China;Gerontology Department,the Second Affiliated Hospital of Harbin Medical University,Harbin 150081,China)

机构地区：[1]哈尔滨医科大学附属第二医院儿内科,哈尔滨150081 [2]哈尔滨医科大学附属第二医院老年医学科,哈尔滨150081

出　　处：《中国医师杂志》2025年第2期318-320,F0003,共4页Journal of Chinese Physician

基　　金：湖北陈孝平科技发展基金会专项基金(CXPJJH123004-038)。

摘　　要：狼疮性肾炎(LN)是系统性红斑狼疮(SLE)最常见的并发症,免疫发病机制与LN的进展和临床治疗密切相关,本综述通过查阅目前国内外免疫细胞在LN发病机制中作用的相关文献,总结分析免疫细胞在LN发病中的致病机制以及相关靶向治疗的研究进展,旨在提高对LN免疫细胞致病机制的认识,完善LN的治疗现状,从而更好地改善患者预后。Lupus nephritis(LN)is the most common complication of systemic lupus erythematosus(SLE).The immune pathogenesis is closely related to the progression and clinical treatment of LN.This review reviews the relevant literature on the role of immune cells in the pathogenesis of LN at home and abroad.This paper summarized and analyzed the pathogenesis of immune cells in the pathogenesis of LN and the research progress of related targeted therapy,aiming to improve the understanding of the pathogenesis of immune cells in LN,improve the treatment status of LN and better improve the prognosis.

关 键 词：狼疮肾炎 免疫细胞 

分 类 号：R59[医药卫生—内科学]