健脾生血片和右旋糖酐铁片对IDA的症状改善情况及铁代谢参数、红细胞参数的影响  

Effects of Jianpi Shengxue Tablets and Dextroanhydride Iron Tablets on IDA Symptom Improvement,Iron Metabolism Parameters and Red Blood Cell Parameters

作　　者：景丽丽 JING Lili(Qingshan District Maternal and Child Health Hospital,Wuhan 430080,China)

机构地区：[1]武汉市青山区妇幼保健院,湖北武汉430080

出　　处：《中外医学研究》2025年第6期15-18,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究健脾生血片和右旋糖酐铁片对妊娠期缺铁性贫血(IDA)的症状改善情况及其对铁代谢参数、红细胞参数的影响。方法:选取2021年1月—2023年12月武汉市青山区妇幼保健院进行产前检查的309名IDA孕妇为研究对象,依据随机数表法分为对照组(n=154)和观察组(n=155)。对照组予以右旋糖酐铁片治疗,观察组予以健脾生血片治疗。比较两组不良妊娠结局发生率、临床疗效、铁代谢参数、临床症状评分、红细胞参数。结果:观察组不良妊娠结局发生率为3.23%,低于对照组的14.29%,差异有统计学意义(P<0.05)。观察组总有效率为92.26%,高于对照组的79.87%,差异有统计学意义(P<0.05)。治疗后,两组铁蛋白(SF)、铁(SI)、转铁蛋白饱和度(TSAT)水平均升高,观察组SF、SI、TSAT水平均高于对照组,差异有统计学意义(P<0.05)。治疗后,两组神疲乏力、心慌胸闷、面色苍白评分均降低,观察组神疲乏力、心慌胸闷、面色苍白评分均低于对照组,差异有统计学意义(P<0.05)。治疗后,两组红细胞计数(RBC)、平均红细胞体积(MCV)、红细胞平均血红蛋白(MCH)均升高,观察组RBC、MCV、MCH均高于对照组,差异有统计学意义(P<0.05)。结论:与右旋糖酐铁片治疗相比,健脾生血片治疗IDA临床疗效显著,能改善IDA孕妇妊娠结局,提高红细胞发育程度,减轻临床症状,并恢复铁代谢。Objective:To study the effects of Jianpi Shengxue tablets and dextroanhydride iron tablets on the improvement of symptoms of iron deficiency anemia(IDA)during pregnancy,iron metabolism parameters and red blood cell parameters.Method:A total of 309 pregnant women with IDA who underwent prenatal examination in Qingshan District Maternal and Child Health Hospital of Wuhan city from January 2021 to December 2023 were selected as the study objects,and were divided into control group(n=154)and observation group(n=155)according to random number table method.The control group was treated with dextran iron tablets,while the observation group was treated with Jianpi Shengxue tablets.The incidence of adverse pregnancy outcome,clinical efficacy,iron metabolism parameters,clinical symptom score and erythrocyte parameters were compared between the two groups.Result:The incidence of adverse pregnancy outcome in observation group was 3.23%,which was lower than that in control group(14.29%),and the difference was statistically significant(P<0.05).The total effective rate of observation group was 92.26%,which was higher than that of control group(79.87%),and the difference was statistically significant(P<0.05).After treatment,serum ferritin(SF),serum iron(SI)and transferrin saturation(TSAT)levels of both groups were increased,and the SF,SI and TSAT levels of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).After treatment,the scores of mental fatigue,palpidity chest tightness and pale face were decreased in both groups,and the scores of mental fatigue,palpidity chest tightness and pale face in the observation group were lower than those in the control group,with statistical significance(P<0.05).After treatment,red blood cell count(RBC),mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),increased and the observation group were higher than control group,and the differences were statistically significant(P<0.05).Conclusion:Compared with dextrose-an

关 键 词：健脾生血片 右旋糖酐铁片 妊娠期缺铁性贫血 妊娠结局 铁代谢参数 

分 类 号：R714.254[医药卫生—妇产科学]