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作 者:蔡真真 洪国灿 张秉贤 CAI Zhenzhen;HONG Guocan;ZHANG Bingxian(Mindon Hospital Affiliated to Fujian Medical University,Fu’an 355000,China;不详)
机构地区:[1]福建医科大学附属闽东医院,福建福安355000
出 处:《中外医学研究》2025年第6期126-129,共4页CHINESE AND FOREIGN MEDICAL RESEARCH
基 金:福建中医药大学校管科研课题项目(XB2021062)
摘 要:目的:研究自拟活血通络方加减内服联合中医针灸治疗腰椎间盘突出症(LDH)的效果。方法:选取2021年7月—2023年11月福建医科大学附属闽东医院收治的80例LDH患者,随机分为对照组、研究组,每组各40例。对照组予以双氯芬酸钠缓释胶囊+针灸治疗,研究组在其基础上联合自拟活血通络方治疗。于治疗前后,对比视觉模拟量表(VAS)、腰臀腿红外热成像值的变化、骨科协会评估治疗分数(JOA),C反应蛋白(CRP)、白介素-6(IL-6),并评价疗效,观察其不良反应。结果:研究组治疗总有效率较对照组高,差异有统计学意义(P<0.05);治疗后,研究组VAS评分明显低于对照组,JOA评分高于对照组,差异有统计学意义(P<0.05)。治疗后,研究组血浆指标较对照组降低更明显,差异有统计学意义(P<0.05);治疗后,红外热成像差值方面,研究组效果更为显著,差异有统计学意义(P<0.05)。两组均未出现明显不良反应症状。结论:自拟活血通络方加减联合针灸对LDH近期的临床疗效确切,可在抗炎的基础上改善患者腰椎疼痛症状。Objective:To observe the Clinical Effects of an orally administered,modified self-formulated Huoxue Tongluo Decoction in conjunction with traditional Chinese acupuncture for the treatment of lumbar disc herniation(LDH).Method:A total of 80 LDH patients admitted to Mindon Hospital Affiliated to Fujian Medical Unversity from July 2021 to November 2023 were randomly divided into control group and study group with 40 cases each group.The control group was treated with diclofenac sodium sustained-release capsules plus acupuncture and moxibustion,and the study group was treated with self-formulated Huoxue Tongluo Decoction on the basis of it.Before and after treatment,the visual analogue pain scale(VAS),the changes of lumbar,hip and leg infrared thermal imaging values,the Orthopaedic Association evaluation treatment score(JOA),C-reactive protein(CRP),interleukin-6(IL-6)were compared,and the efficacy was evaluated and the adverse reactions were observed.Result:The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,VAS score of the study group was significantly lower than that of the control group,and JOA score was higher than that of the control group,with statistical significance(P<0.05).After treatment,the plasma index in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the difference of infrared thermal imaging was more significant in the study group,and the difference was statistically significant(P<0.05).There were no obvious symptoms of adverse reactions in both groups.Conclusion:The recent clinical efficacy of the self-formulated Huoxue Tongluo Decoction plus acupuncture and moxibustion on LDH is definite,and it can improve the lumbar pain symptoms of patients on the basis of anti-inflammatory.
分 类 号:R274.9[医药卫生—中西医结合]
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