成人代谢相关脂肪性肝病营养管理最佳证据总结  

Best evidence summary for nutritional management in adult with metabolic dysfunction-associated fatty liver disease

作　　者：汪楠 张洁[1,2] 段培蓓 孙珍珍[1] 杨莉 Wang Nan;Zhang Jie;Duan Peibei;Sun Zhenzhen;Yang Li(Department of Nursing,Jiangsu Province Hospital of Chinese Medicine,Nanjing 210029,Jiangsu Province,China;School of Nursing,Nanjing University of Chinese Medicine,Nanjing 210023,Jiangsu Province,China)

机构地区：[1]江苏省中医院护理部,江苏南京210029 [2]南京中医药大学护理学院,江苏南京210023

出　　处：《现代临床护理》2025年第1期59-67,共9页Modern Clinical Nursing

摘　　要：目的 检索汇总并评价成人代谢相关脂肪性肝病(metabolic dysfunction-associated fatty liver disease,MAFLD)营养管理的相关最佳证据,为临床实践提供参考。方法 依据“6S”模型自上而下系统检索美国国家指南库,英国国家卫生与临床优化研究所网站,国际指南协作网,医脉通;美国肝病研究学会,欧洲肝病研究协会,亚太肝病学会,美国临床内分泌学会,意大利肝病协会,欧洲临床营养与代谢学会,美国肠外肠内营养学会,BMJ Best Practice,UpToDate,乔安娜·布里格斯研究所(Joanna Briggs Institute,JBI)循证卫生保健中心数据库,PubMed,Cochrane Library,Web of Science,Embase,CINAHL,中国知网,维普,万方,中国生物医学文献服务系统。文献包括成人MAFLD营养管理相关指南、推荐实践、专家共识、系统评价、证据总结。检索时限为建库至2024年3月1日。由2名研究者独立进行文献质量评价和资料提取,并形成最佳证据。结果 共纳入文献24篇,从评估与目标、膳食模式、饮食结构、膳食补充剂、运动指导、健康教育6个方面提取汇总了36条最佳证据。结论 本研究汇总的最佳证据为成人MAFLD患者的营养管理提供了循证支持,可为制定系统化和全面的营养管理计划提供参考。Objective To summarise the evidence on nutritional management in adults with metabolic dysfunction-associated fatty liver disease(MAFLD),therefore to provide a guidance for clinical practice.Methods According to the“6S”model,literature on the nutritional management in adult MAFLD were retrieved from domestic and international databases and websites,including National Guide Library of the United States,National Institute for Health and Care Excellence,Guidelines International Network,the American Association for the Study of the Liver Disease,Europe Association for the Study of the Liver,Asian Pacific Association for the Study of the Liver,American Association of Clinical Endocrinologists,Italian Association for the Study of the Liver,European Society of Clinical Nutrition and Metabolism,American Society for Parenteral and Enteral Nutrition,BMJ Best Practice,UpToDate,Joanna Briggs Institute(JBI)Evidence database,PubMed,Cochrane Library,Web of Science,Embase,CINAHL,Medlive,CNKI,VIP,Wanfang,China Biology Medicine,from the inception of databases to 1st March,2024.The literature included guidelines,expert consensus,recommended practices,systematic reviews and evidence summaries.Two researchers independently evaluated the quality of literature and extracted data to summarise the best evidence.Results A total of 24 publication were finally included,with 36 pieces of best evidence summarised,covering six themes:assessment and goals,dietary patterns,diet structure,dietary supplements,exercise guidance and health education.Conclusion The best evidence on nutritional management summarised in this study provides the evidence-based support for healthcare providers with better nutritional management for adult MAFLD,it also offers a guidance in formulation of individualised nutritional management plans.

关 键 词：代谢相关脂肪性肝病 成人 饮食 营养管理 证据总结 循证护理 

分 类 号：R473.5[医药卫生—护理学]