基于系统评价的二陈汤加减方治疗儿童咳嗽变异性哮喘的疗效及安全性研究  

Efficacy and Safety of Er Chen Tang Plus and Minus Formula for the Treatment of Cough Variant Asthma in Children Based on Systematic Evaluation

作　　者：徐方蔚 姚翠婵 XU Fang-wei;YAO Cui-chan(Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou Guangdong 510620,China)

机构地区：[1]广州医科大学附属广州市妇女儿童医疗中心,广东广州510620

出　　处：《湖北科技学院学报(医学版)》2025年第2期133-137,141,共6页Journal of Hubei University of Science and Technology(Medical Sciences)

摘　　要：目的基于从痰论治的理论,对二陈汤为基本方治疗咳嗽变异性哮喘(CVA)的临床试验进行Meta分析,为其治则治法及临床疗效提供循证医学证据。方法全面搜索国内外公开发表的以二陈汤为基本方治疗CVA的临床试验,进行文献筛选和数据提取,应用Cochrane系统评价方法,对其临床总疗效、患儿随访期间复发率等进行Meta分析。结果二陈汤加减方治疗儿童CVA在临床总疗效优于单纯西医治疗;同时,采用二陈汤加减单用或联合西医治疗后复发率较低。结论从痰论治儿童CVA在临床具有一定准确性和合理性。Objective Based on the theory of phlegm-based treatment,a meta-analysis was conducted on the clinical randomized controlled trials of using Er Chen Tang as the basic formula for treating cough variant asthma(CVA),to provide evidence-based medical evidence of its treatment principle and therapeutic efficacy.Methods We comprehensively searched for domestic and overseas published clinical trials on the treatment of CVA with Er Chen Tang as the basic formula,conducted literature screening and data extraction,and applied the Cochrane systematic evaluation method to conduct meta-analysis on the total clinical efficacy,recurrence rate during the follow-up period of the affected children,and so on.Results The treatment of CVA in children with Er Chen Tang plus and minus formula was better than the treatment with western medicine alone in terms of total clinical efficacy,at the same time,the relapse rate was lower after using Er Chen Tang plus and minus treatment alone or in combination with western medicine.Conclusion The phlegm-based treatment of CVA in children has certain accuracy and rationality in clinical treatment.

关 键 词：咳嗽变异性哮喘 二陈汤 中医药 儿童 META分析 

分 类 号：R725.6[医药卫生—儿科]