基于叶天士络病理论探讨中医药治疗局灶节段性肾小球硬化  

Study on the treatment of focal segmental glomerulosclerosis with traditional Chinese medicine based on Ye Tianshi’s collateral disease theory

作　　者：赵京 邢海涛[1] 赵菁莉[1] ZHAO Jing;XING Hai-tao;ZHAO Jing-li(National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China)

机构地区：[1]天津中医药大学第一附属医院,国家中医针灸临床医学研究中心,天津300381

出　　处：《时珍国医国药》2025年第1期109-113,共5页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(81973799)。

摘　　要：局灶节段性肾小球硬化是目前最常见的难治性肾病综合征的病理类型之一,目前临床尚无系统治疗方案。文章以叶天士络病理论为基础,通过梳理《临证指南医案》的相关医案,基于“络以通为用”的治疗原则,针对局灶节段性肾小球硬化的病因病机和疾病特点,从虚、瘀着手,谈及了补虚通络、辛畅通络、虫蚁剃络等方法,为局灶节段性肾小球硬化的治疗提供新的思路。Focal segmental glomerulosclerosis(FSGS)is one of the most common pathological types of refractory nephrotic syndrome(RNS),and there is no systematical treatment plan in clinical practice so far.Based on Ye TianShi’s collateral disease theory,this paper combs relevant case studies from Case Records as a Guide to Clinical Practice(Linzheng Zhinan Yi’an),and following the treatment principle of“Collaterals should be unblocked”,explores the etiology,pathogenesis,and disease characteristics of FSGS.Focusing on deficiency and blood stasis,the paper addresses these issues by discussing methods such as tonifying deficiency and unblocking collaterals,using aromatic medicinals to open collaterals,and employing insect and ant-based therapies to clear collaterals,aiming to provide new perspectives for the treatment of FSGS.

关 键 词：局灶节段性肾小球硬化 叶天士 络病理论 络脉 中医药 

分 类 号：R256.5[医药卫生—中医内科学]