2021年甘肃省大骨节病患者治疗效果分析  

Treatment effectiveness for Kashin-Beck disease in Gansu Province in 2021

作　　者：费秀兰 陈晓燕[1] 王燕玲[1] 陈国华[1] 何爱伟 李萍[1] Fei Xiulan;Chen Xiaoyan;Wang Yanling;Chen Guohua;He Aiwei;Li Ping(Department of Endemic Disease,Gansu Provincial Center for Disease Control and Prevention,Lanzhou 730000,China)

机构地区：[1]甘肃省疾病预防控制中心地方病防制科,兰州730000

出　　处：《中华地方病学杂志》2025年第1期52-56,共5页Chinese Journal of Endemiology

基　　金：甘肃省科技计划项目(22JR5RA714);兰州市人才创新创业项目(2021-RC-110)。

摘　　要：目的评估甘肃省成人大骨节病(KBD)患者治疗效果,为合理、有效治疗KBD患者提供指导依据。方法以参加甘肃省《2021年基本公共卫生服务补助重点地方病防治项目》(简称项目)的KBD患者为研究对象,分析所有对象性别、年龄、临床分度以及治疗方案选择情况,评估不同地区KBD患者治疗效果。结果共纳入参加治疗项目的KBD患者6711例,其中,男性3139例(46.8%)、女性3572例(53.2%);≤60岁患者3157例(47.0%),>60岁患者3554例(53.0%);Ⅰ、Ⅱ、Ⅲ度患者分别为3921、2166、624例,占比依次为58.4%、32.3%、9.3%。不同地区纳入KBD患者性别、年龄构成及临床分度比较,差异均有统计学意义(χ^(2)=194.34、47.44、408.61,均P<0.001)。治疗方案分布中,选用"药物治疗""药物治疗联合物理疗法""药物治疗联合针灸/按摩""药物治疗联合针灸/按摩联合物理疗法""其他治疗方案"的患者分别为4084(60.9%)、726(10.8%)、672(10.0%)、443(6.6%)、786例(11.7%);不同地区治疗方案分布比较,差异有统计学意义(χ^(2)=1088.38,P<0.001)。KBD患者治疗总有效率为84.5%(5668/6711),不同临床分度KBD患者总有效率从高到低依次为Ⅲ度(87.3%,545/624)、Ⅱ度(86.4%,1871/2166)、Ⅰ度(82.9%,3252/3921);不同治疗方案KBD患者总有效率从高到低依次为"药物治疗联合针灸/按摩联合物理疗法"(91.0%,403/443)、"药物治疗联合物理疗法"(87.1%,632/726)、"药物治疗"(86.7%,3539/4084)、"药物治疗联合针灸/按摩"(82.3%,553/672)、"其他治疗方案"(68.8%,541/786);不同地区KBD患者总有效率由高到低依次为临夏回族自治州(100%,144/144)、庆阳市(88.7%,3562/4017)、平凉市(85.0%,1327/1562)、甘南藏族自治州(83.9%,78/93)、定西市(70.9%,151/213)、天水市(62.5%,125/200)、陇南市(58.3%,281/482)。不同临床分度、治疗方案及地区KBD患者治疗总有效率比较,差异均有统计学意义(χ^(2)=16.95、181.72、435.80,均P<0.001)。结论甘肃省KBD患者治疗�Objective To evaluate the therapeutic effectiveness of adult patients with Kashin-Beck disease(KBD)in Gansu Province,and provide guidance for rational and effective treatment of KBD patients.Methods The KBD patients who participated in the"2021 Basic Public Health Service Subsidy Key Endemic Disease Prevention and Control Project"in Gansu Province were selected as the research subjects.Gender,age,clinical grading characteristics,and treatment plan selection of all subjects were analyzed,and the treatment effectiveness of KBD patients in different regions was evaluated.Results A total of 6711 KBD patients were included in the treatment program,including 3139 males(46.8%)and 3572 females(53.2%),3157 cases(47.0%)of patients aged 60 and 3554 cases(53.0%)over 60 years old.There were 3921,2166,and 624 patients with gradesⅠ,Ⅱ,andⅢ,respectively,accounting for 58.4%,32.3%,and 9.3%,respectively.The gender,age composition,and clinical grading among KBD patients included in different regions were compared,and the differences were statistically significant(χ^(2)=194.34,47.44,408.61,P<0.001).In the distribution of treatment schemes,the number of patients who selected"drug treatment","drug treatment combined with physical therapy","drug treatment combined with acupuncture and moxibustion/massage","drug treatment combined with acupuncture and moxibustion/massage combined with physical therapy",and"other treatment schemes"were 4084(60.9%),726(10.8%),672(10.0%),443(6.6%),and 786(11.7%),respectively.The distribution of treatment plans in different regions was compared,and the difference was statistically significant(χ^(2)=1088.38,P<0.001).The total effective rate of KBD patients was 84.5%(5668/6711).The total effective rates of KBD patients with different clinical grades were ranked from high to low as gradeⅢ(87.3%,545/624),gradeⅡ(86.4%,1871/2166),and gradeⅠ(82.9%,3252/3921).The total effective rate of KBD patients with different treatment schemes from high to low was"drug treatment combined with acupuncture and moxib

关 键 词：大骨节病 成人 治疗效果 

分 类 号：R684.1[医药卫生—骨科学]