Acostream血栓抽吸装置在急性中高危肺栓塞治疗中的应用  

Application of Acostream thrombus suction device in the treatment of acute medium-high risk pulmonary embolism

作　　者：郑祥坚 李春孟 ZHENG Xiangjian;LI Chunmeng(Dingli Clinical Hospital of Wenzhou Medical University,Department of Vascular Surgery,Wenzhou Central Hospital,Wenzhou Pan Vascular Disease Management Center Laboratory,Wenzhou 325000,Zhejiang,China)

机构地区：[1]温州医科大学定理临床学院,温州市中心医院血管外科,温州市泛血管疾病管理中心实验室,浙江温州325000

出　　处：《中国现代医生》2025年第5期49-52,共4页China Modern Doctor

摘　　要：目的探讨Acostream血栓抽吸装置治疗急性中高危肺栓塞的安全性和有效性。方法选取2022年6月至2024年1月于温州市中心医院使用Acostream血栓抽吸装置治疗的10例中高危肺栓塞患者作为研究对象,收集术前、术后72h生命体征及辅助检查等临床观察指标,记录症状缓解情况及并发症情况。评估Acostream血栓抽吸装置清除肺动脉内血栓的安全性和疗效。术后第1、2、3个月随访评估患者的呼吸情况及并发症情况。结果所有患者均通过Acostream血栓抽吸装置完成手术,1例患者因感染性休克加重转重症监护室3d后自动出院,余9例患者呼吸费力等症状均明显改善。患者术后72h动脉血氧分压、指脉氧、心率、肌钙蛋白Ⅰ、N末端B型利钠肽、D二聚体、右心室与左心室内径比值较术前明显改善,差异均有统计学意义(P<0.05)。随访期间1例患者因停用抗凝药病情复发。结论Acostream血栓抽吸装置治疗中高危肺栓塞安全、有效,有较高的临床应用价值。Objective To investigate the safety and effectiveness of Acostream thrombus suction device in the treatment of acute medium-high risk pulmonary embolism(APE).Methods Ten patients with APE medium-high risk treated with Acostream thrombus suction device in Wenzhou Central Hospital from June 2022 to January 2024 were selected as subjects.Clinical observation indicators such as vital signs and auxiliary examination before surgery and 72h after surgery were collected to record the relief of symptoms and complications.The safety and efficacy of the Acostream thrombus suction device for thrombus removal in the pulmonary arteries were evaluated.Respiratory status and complications were assessed at the 1,2 and 3 months.Results All patients completed the operation through the Acostream thrombus suction device.One patient was transferred to the Intensive Care Unit after 3d of automatic discharge because of the septic shock aggravation,and the remaining 9 patients showed significant improvement in strenuous breathing and other symptoms.At 72h after surgery,arterial blood oxygen partial pressure,finger pulse oxygen,heart rate,troponinⅠ,N-terminal prohormone of brain natriuretic peptide,D dimer,and right ventricular ratio to left ventricular diameter of patients were improved compared with preoperative value,and the difference was statistically significant(P<0.05).During the follow-up period,one patient relapsed due to the withdrawal of anticoagulants.Conclusion Acostream thrombus suction device is safe,effective,and has high clinical application value in the treatment of medium-high risk APE.

关 键 词：Acostream血栓抽吸装置 急性中高危肺栓塞 经皮负压血栓抽吸 

分 类 号：R615[医药卫生—外科学]