儿童糖尿病酮症酸中毒发生急性肾损伤2例报告并文献复习  

Report of two cases of acute kidney injury in children with diabetic ketoacidosis and literature review

作　　者：俞蕾 YU Lei(Department of Nephrology,the First People's Hospital of Urumqi(Children's Hospital of Urumqi),Xinjiang Uygur Autonomous Region,Urumqi 830002,China)

机构地区：[1]乌鲁木齐市第一人民医院(乌鲁木齐儿童医院)肾脏科,新疆乌鲁木齐830002

出　　处：《中国当代医药》2025年第4期148-151,共4页China Modern Medicine

基　　金：新疆维吾尔自治区科技厅“天山英才”培养计划(2022TS YCJC0058)。

摘　　要：儿童1型糖尿病和急性肾损伤是全球重要的公共健康问题,危害儿童健康。糖尿病酮症酸中毒是1型糖尿病中常见的急性并发症之一,主要表现为高血糖、酮症和酸中毒。糖尿病酮症酸中毒引发急性肾损伤的原因众多,临床会导致慢性肾脏病的发生,危害患者生命安全。本文报道了2例1型糖尿病酮症酸中毒伴有急性肾损伤患儿的临床资料,并复习文献。通过探讨1型糖尿病患儿发生酮症酸中毒临床特点和急性肾损伤危险因素,进一步加深相关认知,帮助临床医师早期识别和评估,改善预后。Type 1 diabetes and acute kidney injury in children are important public health problems in the world,endangering children's health.Diabetic ketoacidosis is one of the common acute complications of type 1 diabetes,mainly manifested as hyperglycemia,ketoacidosis and acidosis.There are many causes of acute kidney injury caused by diabetic ketoacidosis,which can lead to the occurrence of chronic kidney disease and endanger the life safety of patients.This paper reported the clinical data of two children with type 1 diabetic ketoacidosis complicated with acute kidney injury,and reviewed the literature.By exploring the clinical characteristics of ketoacidosis and risk factors of acute kidney injury in children with type 1 diabetes,we can further deepen the relevant cognition,help clinicians to identify and evaluate early and improve the prognosis.

关 键 词：儿童 糖尿病酮症酸中毒 急性肾损伤 并发症 

分 类 号：R587.1[医药卫生—内分泌]