纤维支气管镜在小儿肺炎支原体感染中的应用效果研究  

Study on application effect of fiberoptic bronchoscopy in children with Mycoplasma pneumoniae infection

作　　者：洪艳 颜孙言 HONG Yan;YAN Sun-yan(Department of Pediatrics,Jinjiang Hospital(Fujian Hospital of Shanghai Sixth People's Hospital),Quanzhou 362200,China)

机构地区：[1]晋江市医院(上海市第六人民医院福建医院)儿科,362200

出　　处：《中国现代药物应用》2025年第4期45-47,共3页Chinese Journal of Modern Drug Application

摘　　要：目的研究小儿肺炎支原体感染运用纤维支气管镜治疗的临床疗效。方法120例肺炎支原体感染患儿,依据随机数表法分为对照组与观察组,每组60例。对照组采用药物对症治疗,观察组在对照组的基础上增加纤维支气管镜治疗。比较两组患儿病症改善时间、炎性因子表达水平以及肺功能指标。结果观察组患儿的咳嗽、咳痰、气促、肺部啰音改善时间分别为(3.42±0.71)、(3.18±0.61)、(3.36±0.28)、(3.18±0.19)d,均短于对照组的(5.48±0.65)、(5.67±0.52)、(5.72±0.41)、(5.70±0.21)d(P<0.05)。治疗后,两组患儿的C反应蛋白、降钙素原与治疗前比较均降低,且观察组患儿的C反应蛋白(5.18±1.14)mg/L、降钙素原(0.42±0.07)ng/ml均低于对照组的(7.13±1.26)mg/L、(0.85±0.04)ng/ml(P<0.05)。治疗后,两组患儿的呼气峰流速、第1秒用力呼气容积占预计值的百分比、用力肺活量均较治疗前升高,且观察组患儿的呼气峰流速(300.84±22.14)L/min、第1秒用力呼气容积占预计值的百分比(81.48±4.22)%、用力肺活量(2.48±0.79)L均高于对照组的(260.98±20.07)L/min、(74.45±4.16)%、(2.06±0.31)L(P<0.05)。结论在小儿肺炎支原体感染的临床治疗中,用纤维支气管镜实施支气管肺泡灌洗治疗的效果理想,更有利于在短时间内缓解病症,减轻炎症反应,改善患儿的肺功能,值得推广。Objective To study the clinical efficacy of fiberoptic bronchoscopy in children with Mycoplasma pneumoniae infection.Methods 120 children with Mycoplasma pneumoniae infection were divided into a control group and an observation group by random numerical table,each with 60 cases.The control group received drug symptomatic treatment,and the observation group received fiberoptic bronchoscopy treatment based on the control group.The improvement time of symptoms,expression level of inflammatory factors and lung function indicators of the two groups were compared.Results The improvement time of cough,sputum,shortness of breath and pulmonary rales in the observation group were(3.42±0.71),(3.18±0.61),(3.36±0.28)and(3.18±0.19)d,which were shorter than(5.48±0.65),(5.67±0.52),(5.72±0.41)and(5.70±0.21)d in the control group(P<0.05).After treatment,the levels of C-reactive protein and procalcitonin in both groups were decreased compared with before treatment;the levels of C-reactive protein and procalcitonin were(5.18±1.14)mg/L and(0.42±0.07)ng/ml in the observation group,which were lower than(7.13±1.26)mg/L and(0.85±0.04)ng/ml in the control group(P<0.05).After treatment,the peak expiratory flow rate,forced expiratory volume in one second as a percentage of the predicted value,and forced vital capacity in both groups were higher than those before treatment;in the observation group,the peak expiratory flow rate was(300.84±22.14)L/min,the forced expiratory volume in one second as a percentage of the predicted value was(81.48±4.22)%,and the forced vital capacity was(2.48±0.79)L,which were higher than(260.98±20.07)L/min,(74.45±4.16)%,and(2.06±0.31)L in the control group(P<0.05).Conclusion In the clinical treatment of Mycoplasma pneumoniae infection in children,the treatment of bronchoalveolar lavage is more ideal.This treatment is more conducive to relieving the disease in a short time,alleviating the inflammatory response,and improving the lung function of children,which is worthy of promotion.

关 键 词：纤维支气管镜 药物对症治疗 小儿肺炎支原体感染 临床疗效 

分 类 号：R725.6[医药卫生—儿科]