探讨自拟三联疗法治疗带状疱疹后遗神经痛的临床疗效  

The clinical efficacy of self-made triple therapy in the treatment of postherpetic neuralgia

作　　者：何良春 曾艳 HE Liang-chun;ZENG Yan(Huichang County Skin Disease Prevention and Treatment Institute,Ganzhou 342600,China)

机构地区：[1]会昌县皮肤病防治所,342600 [2]赣州市皮肤病医院皮肤二科,341000

出　　处：《中国现代药物应用》2025年第4期152-155,共4页Chinese Journal of Modern Drug Application

摘　　要：目的观察自拟三联疗法治疗带状疱疹后遗神经痛的临床疗效。方法66例带状疱疹后遗神经痛患者,以随机数字表法分为对照组与研究组,每组33例。对照组采取常规西药(甲钴胺片+普瑞巴林)治疗,研究组在对照组基础上采取自拟三联疗法(刺络放血+局部拔罐+神灯局部照射)治疗。比较两组临床疗效及治疗前后不同时间段[治疗前(T0)、治疗1个疗程时(T1)、疗程结束后(T2)、治疗结束后3个月(T3)、治疗结束后6个月(T4)]疼痛评分,睡眠障碍评分及疼痛发作频率。结果研究组T0、T1、T2、T3、T4时的疼痛评分分别为(7.94±1.82)、(3.55±0.61)、(2.13±0.49)、(1.73±0.36)、(0.85±0.23)分,睡眠障碍评分分别为(16.53±2.93)、(11.53±2.77)、(8.01±2.62)、(6.34±1.15)、(5.52±1.04)分,疼痛发作频率分别为(30.45±3.42)、(18.30±4.22)、(11.22±2.24)、(5.18±1.16)、(2.13±0.11)次/d。对照组T0、T1、T2、T3、T4时的疼痛评分分别为(8.02±1.83)、(4.67±0.77)、(3.01±0.76)、(2.66±0.15)、(1.78±0.35)分,睡眠障碍评分分别为(16.66±1.97)、(13.66±2.97)、(10.73±2.71)、(8.82±1.83)、(7.33±1.29)分,疼痛发作频率分别为(30.44±3.39)、(22.41±5.27)、(20.33±2.26)、(8.26±2.20)、(3.22±0.47)次/d。T1、T2、T3、T4时,两组患者疼痛评分、睡眠障碍评分及疼痛发作频率均较T0时降低,且研究组患者疼痛评分、睡眠障碍评分及疼痛发作频率较对照组更低,差异有统计学意义(P<0.05)。研究组总有效率96.97%较对照组的75.76%更高,差异有统计学意义(P<0.05)。结论带状疱疹后遗神经痛以自拟三联疗法进行治疗,可减轻患者疼痛与睡眠障碍严重程度,减少疼痛发作频率,提升治疗效果,效果理想。Objective To observe the clinical efficacy of self-made triple therapy in the treatment of postherpetic neuralgia.Methods 66 patients with postherpetic neuralgia were divided into control group and study group by random numerical table,with 33 cases in each group.The control group was treated with conventional Western medicine(mecobalamin tablets+pregabalin),and the study group was treated with self-made triple therapy(blood letting puncture+local cupping+local irradiation with magic lamp)on the basis of the control group.Both groups were compared in terms of clinical efficacy,pain scores at different time periods[(before treatment(T0),during 1 course of treatment(T1),after treatment(T2),3 months after treatment(T3),6 months after treatment(T4)]before and after treatment,sleep disorder score and pain attack frequency.Results In the study group,the pain scores at T0,T1,T2,T3 and T4 were(7.94±1.82),(3.55±0.61),(2.13±0.49),(1.73±0.36)and(0.85±0.23)points,the sleep disorder scores were(16.53±2.93),(11.53±2.77),(8.01±2.62),(6.34±1.15)and(5.52±1.04)points,the pain attack frequency were(30.45±3.42),(18.30±4.22),(11.22±2.24),(5.18±1.16)and(2.13±0.11)attacks/d;in the control group,the pain scores at T0,T1,T2,T3 and T4 were(8.02±1.83),(4.67±0.77),(3.01±0.76),(2.66±0.15)and(1.78±0.35)points,the sleep disorder scores were(16.66±1.97),(13.66±2.97),(10.73±2.71),(8.82±1.83)and(7.33±1.29)points,and the pain attack frequency were(30.44±3.39),(22.41±5.27),(20.33±2.26),(8.26±2.20)and(3.22±0.47)attacks/d.At T1,T2,T3 and T4,the pain score,sleep disorder score and pain attack frequency in both groups were lower than those at T0,and the pain score,sleep disorder score and pain attack frequency in the study group were lower than those in the control group.The difference was statistically significant(P<0.05).The total effective rate of 96.97%in the study group was higher than 75.76%in the control group,and the difference was statistically significant(P<0.05).Conclusion The self-made triple therapy for posthe

关 键 词：自拟三联疗法 带状疱疹后遗神经痛 疼痛评分 睡眠障碍评分 

分 类 号：R75[医药卫生—皮肤病学与性病学]