无水乙醇灌洗硬化治疗肾囊肿的疗效及对患者术后疼痛情绪的影响  

Curative effect of anhydrous ethanol lavage sclerotherapy for renal cyst and its influence on patients'postoperative pain and emotions

作　　者：赵晓 沙文 纪传彪 Zhao Xiao;Sha Wen;Ji Chuanbiao(Puyang Oilf ield General Hospital,Puyang 457001,Henan,China)

机构地区：[1]濮阳油田总医院,河南濮阳457001

出　　处：《临床心身疾病杂志》2025年第2期23-27,40,共6页Journal of Clinical Psychosomatic Diseases

基　　金：濮阳市科技计划项目(编号1805040)。

摘　　要：目的 探究超声引导下穿刺抽液联合无水乙醇灌洗硬化治疗肾囊肿的疗效及对患者术后疼痛、情绪的影响。方法 将80例肾囊肿患者按照治疗方法分为对照组38例和联合组42例。对照组采用超声引导下穿刺抽液术治疗,联合组在对照组基础上联合无水乙醇灌洗硬化治疗,术后随访12个月。比较两组患者疗效、肾囊肿改变情况、肝肾功能、不良反应及复发情况,术前及术后24 h视觉模拟评分法(VAS)评分,术前及出院时焦虑自评量表(SAS)、抑郁自评量表(SDS)评分。结果 联合组患者临床疗效总有效率高于对照组(P<0.05)。两组患者术后24 h的VAS评分及出院时SAS和SDS评分比较,差异均无统计学意义(P>0.05)。术后3个月、6个月联合组患者囊肿最大径小于对照组,囊肿体积缩小率高于对照组(P<0.05或0.01)。手术前后两组患者肝肾功能指标无明显变化,组间比较差异也无统计学意义(P>0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。术后12个月联合组患者复发率低于对照组(P<0.01)。结论 超声引导下穿刺抽液联合无水乙醇灌洗硬化治疗肾囊肿疗效确切,未增加患者术后疼痛及负性情绪,对肝肾功能影响小,复发率相对较低,值得临床推广。Objective To explore the curative effect of ultrasound-guided puncture extraction plus anhydrous ethanol lavage sclerotherapy for renal cyst and its influence on patients'postoperative pain and emotions.Methods Eighty renal cysts patients were divided into control(n=38)and combination(n=42)group according to treatment methods.Controls received ultrasound-guided puncture extraction treatment,combination group was plus anhydrous ethanol lavage sclerotherapy on the basis of controls,and post-operative follow-up was 12 months.Such indexes were compared between two groups as curative effects,renal cysts changes,hepatic and renal function,adverse reactions,and recurrence,pre-and post-operative Visual Analogue Scale(VAS)scores,per-operative and at discharge Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)scores.Results Clinically total effective rate was higher in combination than control group(P<0.05).Intergroup differences in postoperative 24th hour VAS as well as SAS and SDS score at discharge weren't statistically significant(P>0.05).The maximum cyst diameters in the 3rd and 6th month after surgery were smaller and the reduction rate of cyst volume was higher in combination than control group(P<0.05 or 0.01).Pre-and postoperative hepatic and renal function indicators had no signif icant changes in both groups,thei r intergroup differences weren't statistically significant(P>0.05).Intergroup difference in incidence rates of adverse reactions wasn't statistically significant(P>0.05).In the 12th month after surgery,the recurrence rate was lower in combination than control group(P<0.01).Conclusion Ultrasound-guided puncture dra inage combined with anhydrous ethanol lavage sclerotherapy has an exact efficacy in the treatment of renal cysts,doesn't increase postoperative pain and negative emotions,has little influence on hepatic and renal function and relatively lower recurrence rate,and it is worthy of clinical promotion.

关 键 词：超声引导下穿刺抽液 无水乙醇灌洗硬化 肾囊肿 疗效 疼痛 情绪 

分 类 号：R692.12[医药卫生—泌尿科学]