冠心病患者合并焦虑/抑郁的危险因素分析及中医证候特征  

Risk factors of coronary heart disease patients combined with anxiety/depression and characteristics of TCM syndromes

作　　者：马英歌[1] 胡海军[2] 张晓南[1] 管文娟[3] Ma Yingge;Hu Haijun;Zhang Xiaonan;Guan Wenjuan(Anyang District Hospital of Puyang City,Anyang 455000,Henan,China;不详)

机构地区：[1]濮阳市安阳地区医院,河南安阳455000 [2]安阳市第五人民医院,河南安阳455000 [3]濮阳市人民医院,河南濮阳457000

出　　处：《临床心身疾病杂志》2025年第2期88-93,共6页Journal of Clinical Psychosomatic Diseases

基　　金：河南省医学科技攻关计划联合共建项目(编号LHGJ20200914)。

摘　　要：目的 探讨冠心病患者合并焦虑/抑郁的危险因素及中医证候特征。方法 将96例冠心病合并焦虑/抑郁患者设为研究组,无焦虑/抑郁的96例冠心病患者设为对照组。采用单因素分析及Logistic回归分析探讨冠心病患者发生焦虑/抑郁的危险因素,并分析研究组患者中医证候分布情况。结果 Logistic回归分析结果显示,女性、冠心病病程、冠心病每次发作持续时间、便秘均是冠心病患者合并焦虑的危险因素(P<0.05或0.01);年龄、冠心病病程、冠心病每次发作持续时间、吸烟史、便秘均是冠心病患者合并抑郁的危险因素(P<0.05或0.01)。96例冠心病患者中,单纯合并焦虑者以气滞血瘀证、心血瘀阻证为主要证候;单纯合并抑郁和合并焦虑抑郁者以气滞血瘀证、气虚血瘀证为主要证候。结论 冠心病患者合并焦虑/抑郁的病因病机复杂,危险因素较多,中医证候以气滞血瘀证为主,临床应根据危险因素及中医证候对其予以针对性干预。Objective To explore the risk factors of coronary heart disease(CHD)patients combined with anxiety/depression and characteristics of TCM syndromes.Methods Ninety-six CHD patients with anxiety/depression were set as research and 96 ones without as control group.Single-factor and Logistic regression analysis were used to explore the risk factors of anxiety and/or depression occurrence in CHD patients and the distributions of TCM symptoms analyzed in research group.Results Logistic regression analysis showed that female,course of CHD,CHD duration per episode and constipation were all risk factors for CHD patients with anxiety(P<0.05 or 0.01).Age,course of CHD,CHD duration per episode,smoking history and constipation were all risk factors for CHD patients with depression(P<0.05 or 0.01).Of 96 CHD patients,blood stasis due to Qi sluggishness and the stagnation of heart-blood were main TCM syndrome in patients with simple anxiety;blood stasis due to Qi sluggishness and blood stasis due to Qi deficiency were main syndromes in patients with simple depression and with anxiety and depression.Conclusion The etiology and pathogenesis of CHD patients with anxiety and depression are complex,risk factors are more,blood stasis due to Qi sluggishness is the main syndrome,and targeted intervention should be carried out according to risk factors and TCM syndrome.

关 键 词：冠心病 焦虑 抑郁 中医证候 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病] R241.4[医药卫生—内科学]