早期目标导向活动对连续性肾脏替代患者活动能力和血生化指标的影响  

Effect of early goal-directed activities on the mobility and blood biochemical indicators of patients with continuous renal replacement therapy

作　　者：向春草 莫锌锌 梁莎 XIANG Chuncao;MO Xinxin;LIANG Sha(Critical Care Medicine Department,Henan Electric Power Hospital,Zhengzhou 450000,China)

机构地区：[1]河南电力医院重症医学科,河南郑州450000

出　　处：《黑龙江医药科学》2025年第2期35-38,共4页Heilongjiang Medicine and Pharmacy

基　　金：河南省医学科技攻关项目,编号:LHGJ20193094。

摘　　要：目的:探究连续性肾脏替代患者行早期目标导向活动干预后对其活动能力和血生化指标的影响。方法:抽签法将河南电力医院2021年10月至2023年10月收治的97例连续性肾脏替代患者分两组,常规组(n=48例)实施常规干预,干预组(n=49例)在常规组基础上行早期目标导向活动干预,比较两组血生化指标、肌力评分、生活自理能力、活动能力评分和不良安全事件。结果:干预组10 d后ICU活动量表(ICU mobility scale,IMS)评分、英国医学研究委员会(MRC)肌力评分、Barthel指数量表(BI)评分较常规组高,1个月后凝血酶原时间、血小板较常规组低,纤维蛋白原、活化部分凝血活酶时间较常规组高,期间非计划性下机发生率较干预组低,差异有统计学意义(P<0.05)。结论:连续性肾脏替代患者行早期目标导向活动干预可有效改善其血生化指标、活动能力和肌肉力量,减少不良安全事件发生,有利于其生活自理能力的提高。Objective:To explore the effects of early goal-directed activity intervention on the activity ability and blood biochemical indicators of patients with continuous kidney replacement therapy.Methods:97 patients with continuous kidney replacement therapy in Henan Electric Power Hospital from October 2021 to October 2023 were divided into 2 groups using lottery method.The conventional group(n=48 cases)received routine intervention,and the intervention group(n=49 cases)received early goal-directed activity intervention based on the conventional group.Blood biochemical indicators,muscle strength score,self-care ability,activity ability score and adverse safety events were compared between the two groups.Results:After 10 days,the intervention group had higher scores on the ICU Mobility Scale(IMS),the MRC muscle strength score,and the Barthel Index(BI)score than the conventional group.At the end of the month,the prothrombin time and platelet count were lower than those in the conventional group,while fibrinogen and activated partial thromboplastin time were higher.The incidence of unplanned disconnection was lower in the conventional group than in the intervention group,and the difference was statistically significant(P<0.05).Conclusion:Early goal-directed activity intervention in patients with continuous renal replacement therapy can effectively improve their blood biochemical indicators,activity ability and muscle strength,reduce the occurrence of adverse safety events and help improve their self-care ability.

关 键 词：连续性肾脏替代 早期目标导向活动干预 活动能力 血生化指标 

分 类 号：R473.5[医药卫生—护理学]