门冬氨酸钾镁联合倍他乐克、胺碘酮对心梗伴恶性心律失常患者心功能及血液流变学的影响  

Effects of potassium magnesium aspartate combined with betaloc and amiodarone on cardiac function and hemorheology in patients with myocardial infarction and malignant arrhythmia

作　　者：杨楠 李娜 侯艳艳 田惠 YANG Nan;LI Na;HOU Yanyan;TIAN Hui(CCU,Hebi People's Hospital,Hebi 458030,China)

机构地区：[1]鹤壁市人民医院CCU,河南鹤壁458030

出　　处：《黑龙江医药科学》2025年第2期43-46,共4页Heilongjiang Medicine and Pharmacy

基　　金：河南省自然科学基金项目,编号:20221385。

摘　　要：目的:观察门冬氨酸钾镁联合倍他乐克、胺碘酮对心梗伴恶性心律失常患者心功能和血液流变学的影响。方法:按照随机数字表法,对鹤壁市人民医院2021年6月至2023年6月收治的98例心梗伴恶性心律失常患者进行分组,每组纳入49例患者。对照组采用倍他乐克与胺碘酮治疗,观察组采用门冬氨酸钾镁联合倍他乐克、胺碘酮治疗。观察患者心功能与血液流变学变化情况,并统计其疗效表现与不良反应事件发生率。结果:观察组患者经治疗后的LVEF更高,LVEDD与LVPWD更低,患者治疗后的血液流变学指标表现同对照组相比更低,治疗总有效率更高,且不良反应的总发生率更低(P<0.05)。结论:应用门冬氨酸钾镁、倍他乐克与胺碘酮开展联合治疗,有助于强化心梗伴恶性心律失常患者的心功能,改善血液流变学,减少不良反应事件的发生风险,提高临床治疗效果。Objective:To observe the impact of potassium magnesium aspartate combined with betaloc and amiodarone on cardiac function and hemorheology in patients with myocardial infarction and malignant arrhythmia.Methods:98 patients with myocardial infarction and malignant arrhythmia from Hebi People's Hospital were randomized into two groups of 49 patients each based on a random number table.The control group received treatment with betaloc and amiodarone,while the observation group received treatment with potassium magnesium aspartate combined with betaloc and amiodarone.Changes in cardiac function and hemorheology were observed,and the efficacy and incidence of adverse events were recorded.Results:After treatment,patients in the observation group had higher LVEF,lower LVEDD and LVPWD,lower hemorheological indicators,higher overall treatment effectiveness and lower overall incidence of adverse events compared to the control group(P<0.05).Conclusion:The combined use of potassium magnesium aspartate,betaloc and amiodarone can enhance cardiac function,improve hemorheology,reduce the risk of adverse events,and improve clinical treatment outcomes in patients with myocardial infarction and malignant arrhythmia.

关 键 词：门冬氨酸钾镁 倍他乐克 胺碘酮 恶性心律失常 

分 类 号：R542.22[医药卫生—心血管疾病]