全国名老中医傅淑清基于“痰-气-火”论治小儿咳嗽病的用药规律分析  

Medication rules analysis of Fu Shuqing,a national famous expert of traditional Chinese medicine,treating pediatric cough based on“phlegm-qi-fire”

作　　者：吕燕红 孟萍[2] 刘玲贞[3] 高晓静[2] 陈建章[1] 邓棋卫[2] LYU Yanhong;MENG Ping;LIU Lingzhen;GAO Xiaojing;CHEN Jianzhang;DENG Qiwei(Department of Chinese Internal Medicine,Affiliated Hospital of Jiangxi College of Traditional Chinese Medicine,Fuzhou Hospital of Traditional Chinese Medicine,Jiangxi Province,Fuzhou 344000,China;Department of Medicine,Jiangxi College of Traditional Chinese Medicine,Jiangxi Province,Fuzhou 344000,China;Department of Personnel Office,Jiangxi College of Traditional Chinese Medicine,Jiangxi Province,Fuzhou 344000,China)

机构地区：[1]江西中医药高等专科学校附属医院,江西省抚州市中医医院中医内科,江西抚州344000 [2]江西中医药高等专科学校医疗系,江西抚州344000 [3]江西中医药高等专科学校人事处,江西抚州344000

出　　处：《中国当代医药》2025年第5期122-126,共5页China Modern Medicine

基　　金：全国名老中医药专家传承工作室建设项目(国家中医药人教函〔2022〕75号);江西省名老中医药专家传承工作室建设项目(赣中医药科教字〔2022〕11号);江西省教育厅科学技术研究项目(GJJ213306);江西省高等学校教学改革研究省级课题(JXJG-19-44-1);江西中医药高等专科学校旴江医派研究院师承项目(2024XJSC02);江西中医药高等专科学校校级重点科技项目(2022A04)。

摘　　要：目的挖掘全国名老中医傅淑清主任治疗小儿咳嗽病的用药规律及临证经验。方法收集、整理并提取2015年1月至2016年7月傅淑清主任治疗小儿咳嗽病门诊处方数据,运用中医传承计算平台v 3.0对处方数据进行频数、关联规则及聚类分析。结果纳入408首处方共87味中药,药性以寒、温为主;药味以苦、甘、辛为主;涉及12种药物类别,频次前3位为化痰止咳平喘类、清热类、解表类;涉及11条经络,以肺经、心经、脾经为主。关联规则分析显示傅淑清主任用药核心配伍组合为“茯苓-法半夏-川贝母-杏仁-鱼腥草-连翘-甘草”,聚类分析得出关联系数较高的6个新类方。结论傅淑清主任治疗小儿咳嗽以二陈汤合川贝杏仁饮为底方进行灵活化裁,立足肺、心、脾(胃)、肝,从“痰-气-火”关系入手,化痰止咳中重调气降火,善用辛开苦降之法,喜用药对杏仁-桔梗,法半夏-苦杏仁,法半夏-川贝母,鱼腥草-川贝母,组方配伍善用“宣-降-清-润”四法。Objective To find out the medication rules and clinical experience of the national famous traditional Chinese medicine expert Fu Shuqing's treatment of pediatric cough.Methods The outpatient prescription data of Director Fu Shuqing's pediatric cough treatment from January 2015 to July 2016 were collected,sorted out and extracted,and the frequency,association rules and cluster analysis of the prescription data were carried out using traditional Chinese medicine inheritance computing platform v 3.0.Results A total of 87 kinds of drugs were included in 408 prescriptions,and the drug properties were mainly cold and warm.The taste of drugs were mainly bitter,sweet and pungent.There were 12 kinds of drugs involved,and the top 3 were eliminating phlegm,relieving cough and asthma,clearing heat and diaphoresis relieving superficies.A total of 11 channels were involved,mainly lung channel,heart channel and spleen channel.Association rule analysis showed that the core combination of Fu Shuqing's drugs was"Tuckahoe-Pinellinae Rhizoma Praeparatum-Fritillariae Cirrhosae Bulbus-Almond-Houttuyniae Herba-Forsythia Suspensa-Liquorice",and six new prescriptions with high association coefficient were obtained by cluster analysis.Conclusion Director Fu Shuqing used Erchen Decoction and Fritillary and Almond Cough Mixture as the base for the treatment of pediatric cough,based on the lung,heart,spleen(stomach)and liver,starting from the relationship of"phlegm-qi-fire",reregulating qi and reducing fire in resolving cough,making good use of the method of acrid opening and bitter downbearing,and liked to use the medicine of Almond-Platycodonisi Radix,Pinellinae Rhizoma Praeparatum-Armeniacae Semen Amarum,Pinellinae Rhizoma Praeparatum-Fritillariae Cirrhosae Bulbus,Houttuyniae Herba-Fritillariae Cirrhosae Bulbus.Make good use of the four methods of"ascending-descending-clearing-moistening".

关 键 词：小儿咳嗽 数据挖掘 傅淑清 用药规律 

分 类 号：R272[医药卫生—中医儿科学]