先天性颗粒细胞牙龈瘤的临床影像特征分析  

Clinical Imaging Analysis of Congenital Granular Cell Epulis

作　　者：王芮 袁理 曹亚先 周宁 张笑春 WANG Rui;YUAN Li;CAO Yaxian(Department of Radiology,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou Guangdong 510623)

机构地区：[1]广州医科大学附属妇女儿童医疗中心放射科,广东广州510623 [2]广州医科大学附属妇女儿童医疗中心病理科,广东广州510623

出　　处：《医学临床研究》2025年第2期197-199,203,共4页Journal of Clinical Research

基　　金：广州市卫生健康科技项目(编号:20231A011036、20221A011024)。

摘　　要：【目的】探讨新生儿先天性颗粒细胞牙龈瘤(CGCE)的临床影像特点。【方法】回顾性分析2017年6月至2023年2月在本院经手术病理确诊为CGCE的6例患儿的临床资料,分析其临床及影像学特征。【结果】6例患儿肿瘤最大直径1.3~3.4 cm,4例为多发病灶,其中3例累及上下颌牙槽嵴,1例累及上颌牙槽嵴及舌下。2例为单发病灶,分别累及上颌牙槽嵴、下颌牙槽嵴,6例肿瘤内均无出血、坏死囊变及钙化灶。增强扫描由边缘向中央填充式强化2例,逐渐强化3例,扩散加权成像(DWI)上呈稍高信号,表观扩散系数(ADC)图上呈低信号,6例均无邻近骨质受累。【结论】CGCE的影像学表现具有一定的特征,确诊需经病理和免疫组织化学检查。【Objective】To analyze the clinical and imaging finding of in congenital granular cell epulis,and improve the recognition of the disease.【Methods】The clinical data of 6 children diagnosed with CGCE by surgical pathology from June 2017 to February 2023 in our hospital were retrospectively analyzed,and their clinical and imaging characteristics were analyzed.【Results】The maximum tumor diameter of 6 cases was 1.3-3.4 cm,and 4 cases had multiple lesions,of which 3 cases involved both maxillary and mandibular alveolar crista,and 1 case involved both maxillary alveolar crista and sublingual.2 cases had single lesions involving maxillary anterior alveolar ridge and mandibular alveolar ridge,respectively.Necrosis、cystic change and hemorrhage was not seen in 6 cases.Two cases showed filling enhancement from the edge to the center,and 3 cases showed gradual enhancement.The tumors had high signal on DWI,and low signal on ADC map.No adjacent bone was involved in 6 cases.【Conclusions】The imaging findings of CGCE have certain characteristics,and the diagnosis needs to be confirmed by pathological and immunohistochemical examination.

关 键 词：牙龈肿瘤 婴儿 新生 体层摄影术 螺旋计算机 磁共振成像 

分 类 号：R788.3[医药卫生—口腔医学]