二氧化碳点阵激光联合化学换肤治疗面部萎缩性瘢痕的临床观察  

Clinical observation on the treatment of facial atrophic scars by carbon dioxide fractional laser combined with chemical peeling

作　　者：闻娟 薛峰[1] 陈建华 王江允[1] WEN Juan;XUE Feng;CHEN Jianhua;WANG Jiangyun(Department of Dermatological,The Third People's Hospital of Zhengzhou,Zhengzhou 450001,Henan Province,China)

机构地区：[1]郑州市第三人民医院皮肤科,河南郑州450001

出　　处：《中国医疗美容》2025年第2期15-17,共3页China Medical Cosmetology

摘　　要：目的 比较二氧化碳(CO_(2))点阵激光联合化学换肤和点阵激光治疗面部萎缩性瘢痕的疗效。方法 选取2023年1月至2023年12月郑州市第三人民医院皮肤科收治的120例面部萎缩性瘢痕患者,按治疗方法不同分为观察组(采用CO_(2)点阵激光联合化学换肤)和对照组(采用CO_(2)点阵激光),每组60例。采用痤疮瘢痕权重评分(ECCA)评估治疗前、治疗后3个月瘢痕变化,记录两组不良反应情况及治疗后3个月患者整体满意度评分。结果 两组治疗前ECCA评分无统计学差异(P>0.05);观察组治疗后ECCA评分(43.7±4.9)分,对照组治疗评分(52.8±6.7)分,两组治疗前后差异均有统计学意义(P<0.05),治疗后两组ECCA评分差异有统计学意义(P<0.05)。观察组患者满意度88%,对照组为71%,两组差异有统计学意义(P<0.05);观察组发生2例刺痛、1例水肿、1例色素沉着,对照组发生1例刺痛、1例水肿、1例色素沉着,两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论 CO_(2)点阵激光联合化学换肤在改善面部萎缩性瘢痕外观方面效果显著优于单用点阵激光,不良反应发生率低。Objective To compare the effificacy of carbon dioxide(CO_(2))fractional laser combined with chemical peeling and fractional laser alone in the treatment of facial atrophic scars.Methods A total of 120 patients with facial atrophic scars admitted to the Department of Dermatology,the Third People's Hospital of Zhengzhou from January 2023 to December 2023 were selected.They were divided into an observation group(treated with CO_(2) fractional laser combined with chemical peeling)and a control group(treated with CO_(2) fractional laser)according to different treatment methods,with 60 patients in each group.The ECCA scoring system was used to evaluate the changes of scars before treatment and 3 months after treatment.The adverse reactions in both groups and the overall patient satisfaction score 3 months after treatment were recorded.Results There was no signifificant difference in ECCA scores between the two groups before treatment(P>0.05).The ECCA score of the observation group after treatment was(43.7±4.9),and that of the control group was(52.8±6.7).The differences before and after treatment in both groups were statistically signifificant(P<0.05),and the difference in ECCA scores between the two groups after treatment was also statistically signifificant(P<0.05).The patient satisfaction rate in the observation group was 88%,and that in the control group was 71%,with a signifificant difference between the two groups(P<0.05).In the observation group,2 cases of stinging pain,1 case of edema,and 1 case of pigmentation occurred.In the control group,1 case of stinging pain,1 case of edema,and 1 case of pigmentation occurred.There was no signifificant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions CO_(2) fractional laser combined with chemical peeling is signifificantly superior to fractional laser alone in improving the appearance of facial atrophic scars,with a low incidence of adverse reactions.

关 键 词：点阵激光 化学换肤 萎缩性瘢痕 

分 类 号：R622[医药卫生—整形外科]