盘状红斑狼疮的皮肤镜特征及其在鉴别诊断中的应用  

Dermoscopic features of discoid lupus erythematosus and its application in differential diagnosis

作　　者：周翠云 付超 高菲 魏世娟 齐宇萌 张永飞 边培雯[1] 高敏虹[1] 辛琳琳[1,2] ZHOU Cuiyun;FU Chao;GAO Fei;WEI Shijuan;QI Yumeng;ZHANG Yongfei;BIAN Peiwen;GAO Minhong;XIN Linlin(Department of Dermatology and Venereology,Shandong Province Qianfoshan Hospital,The First Affiliated Hospital of Shandong First Medical University,Jinan 250000,China;Jinan Clinical Medical Research Center for Tissue Engineering Skin Regeneration and Wound Repair,Jinan 250000,China)

机构地区：[1]山东第一医科大学第一附属医院,山东省千佛山医院皮肤性病科,山东济南250000 [2]济南市组织工程皮肤再生与创面修复临床医学研究中心,山东济南250000

出　　处：《皮肤病与性病》2025年第1期11-14,共4页Dermatology and Venereology

摘　　要：盘状红斑狼疮(DLE)是一种慢性自身免疫性结缔组织疾病,亦是慢性皮肤型红斑狼疮中最常见的一种类型,后期会遗留萎缩性瘢痕,甚至毁容。盘状红斑狼疮也易与其他头面部炎症性皮肤病相混淆,导致漏诊、误诊。盘状红斑狼疮的诊断是临床难点,目前皮肤活检仍为诊断盘状红斑狼疮的“金标准”,但其有创性会给患者造成一定心理负担。皮肤镜作为一种简单、快捷的无创辅助诊断工具,不仅可用于盘状红斑狼疮的早期诊断与鉴别诊断,还可以从不同部位、轻重程度等方面进行全面分析。本文着重介绍了盘状红斑狼疮皮肤镜学特征及皮肤镜在盘状红斑狼疮诊断与鉴别诊断中的应用。Discoid lupus erythematosus(DLE)is a chronic autoimmune connective tissue disease,it is also the most common type of chronic cutaneous lupus erythematosus(CCLE),which can lead to atrophic scars and even disfigurement.DLE is also easily confused with other head and face inflammatory skin diseases,leading to missed and wrong diagnosis.Its diagnosis is a clinical difficulty,Skin biopsy is still the gold standard for the diagnosis of DLE at present,but its invasiveness causes a certain psychological burden to patients.Dermoscopy,as a simple,fast and non-invasive auxiliary diagnostic tool,can not only be used for the early diagnosis and differential diagnosis of DLE,but also can be used for comprehensive analysis from different parts and severity.This article focuses on the dermoscopic characteristics of discoid lupus erythematosus and the application of dermoscopy in the diagnosis and differential diagnosis of discoid lupus erythematosus.

关 键 词：盘状红斑狼疮 皮肤镜 诊断 鉴别诊断 

分 类 号：R758.62[医药卫生—皮肤病学与性病学]