苏合香及其复方治疗心脑血管疾病的作用机制研究进展  

Research progress on the mechanism of Styrax and its compound in the treatment of cardio-cerebrovascular diseases

作　　者：马小玲 韩丹 葛卫红[1] 于锋 MA Xiaoling;HAN Dan;GE Weihong;YU Feng(Department of Pharmacy,China Pharmaceutical University Nanjing Drum Tower Hospital,Nanjing 210008,China;School of Basic Medicine and Clinical Pharmacy,China Pharmaceutical University,Nanjing 210009,China;Department of Pharmacy,Nanjing Drum Tower Hospital Affiliated Hospital of Medical School,Nanjing University,Nanjing 210008,China)

机构地区：[1]中国药科大学南京鼓楼医院药学部,南京210008 [2]中国药科大学基础医学与临床药学学院,南京210009 [3]南京大学医学院附属鼓楼医院药学部,南京210008

出　　处：《药学前沿》2025年第2期345-354,共10页China Pharmacist

基　　金：国家自然科学基金青年科学基金项目(81803525)。

摘　　要：心脑血管疾病是危害人类健康最基础和最常见的疾病之一,发病率和致死率逐年上升,给社会经济带来重大负担。基于心脑血管疾病相互影响、多见共存的特点,以及中医整体性和中药多组分、多靶点、多通路的特点,中药单药及复方治疗这类疾病能更好地发挥其优势。苏合香是金缕梅科植物苏合香树所分泌的树脂,具有开窍、辟秽、止痛的功效。苏合香及相关复方,如苏合香丸、冠心苏合丸、麝香保心丸和神香苏合丸被广泛用于治疗心脑血管疾病。本文通过检索苏合香及其复方相关文献,归纳总结苏合香单药及其复方在治疗心脑血管疾病的作用机制,以期给未来的研究方向提供参考,便于相关药物的进一步开发和应用。The cardio-cerebrovascular disease is one of the most basic and common diseases that jeopardize human health,with the incidence and fatality rates increasing year by year,bringing a significant burden to the society and economy.Based on the characteristics of cardio-cerebral diseases interacting with each other and co-existing in many ways,as well as the holistic nature of traditional Chinese medicine and the multi-component,multi-target and multi-pathway characteristics of Chinese medicine,single and compound Chinese medicines can better utilize their advantages in the treatment of such diseases.Styrax is a resin secreted by Styrax arborescens of Hamamelidaceae,which has the effects of inducing resuscitation,eliminating filth and relieving pain.Styrax and related compounds,such as Styrax pills,Guanxin Suhe pills,Shexiang Baoxin pills and Shenxiang Suhe pills are widely used in the treatment of cardiovascular and cerebrovascular diseases.By searching related literature of Styrax and its compounds,the mechanism of Styrax single drug and its compounds in the treatment of cardio-cerebrovascular diseases are summerized in this study,in order to provide a reference for future research direction and facilitate the further development and application of related drugs.

关 键 词：苏合香 苏合香复方 心脑血管疾病 作用机制 研究进展 

分 类 号：R952[医药卫生—药学]