补中益气汤加味联合经尿道等离子前列腺剜除术治疗良性前列腺增生合并逼尿肌收缩力低下临床观察  

Clinical Observation of Modified Center-Supplementing and Qi-Boosting Decoction Combined with Transurethral Plasma Kinetic Enucleation of Prostate in the Treatment of Benign Prostatic Hyperplasia Complicated with Detrusor Underactivity

作　　者：谢世磊 向松涛[1,2] 王志超[2] XIE Shilei;XIANG Songtao;WANG Zhichao(Guangzhou University of Chinese Medicine,Guangzhou,Guangdong,China,510440;Fangcun Hospital of Guangdong Provincial Hospital of Chinese Medicine,Guangzhou,Guangdong,China,510160)

机构地区：[1]广州中医药大学,广东广州510440 [2]广东省中医院芳村医院,广东广州510160

出　　处：《河南中医》2025年第3期425-430,共6页Henan Traditional Chinese Medicine

摘　　要：目的:观察补中益气汤加味联合经尿道等离子前列腺剜除术(plasma kinetic enucleation of prostate,PKEP)治疗良性前列腺增生合并逼尿肌收缩力低下(detrusor underactivity,DU)的临床疗效。方法:选取2022年12月至2023年12月在广东省中医院芳村医院行PKEP术治疗的BPH合并DU患者68例,按照随机数字表法分为对照组35例和治疗组33例。所有患者均行PKEP术,两组患者术后均行常规治疗方案,治疗组在常规治疗的基础上加用补中益气汤加味治疗。观察两组患者临床疗效、围手术期相关并发症及治疗前后IPSS评分、IPSS-V评分、IPSS-S评分、QoL评分、残余尿量(post-void residual urine volume,PVR)、最大尿流率(maximum urine rate,Qmax)变化情况。结果:在手术期间,两组剜除组织重量、术后钠离子、血红蛋白下降、失血量、住院天数、手术时间比较,差异无统计学意义(P>0.05)。两组术后1个月、3个月IPSS评分、IPSS-V评分、IPSS-S评分、QoL、PVR、Qmax均优于治疗前(P<0.05),两组术后1个月、3个月IPSS评分、IPSS-V评分、IPSS-S评分、QoL、PVR比较,差异无统计学意义(P>0.05),观察组术后1个月、3个月Qmax低于对照组,差异有统计学意义(P<0.05)。治疗组有效率为78.79%,对照组有效率为82.86%,两组有效率比较,差异无统计学意义(P>0.05)。结论:补中益气汤加味联合PKEP手术治疗良性前列腺增生合并逼尿肌收缩力低下,可以改善患者症状和生活质量,提升患者术后Qmax。Objective:To observe the clinical efficacy of Modified Center-Supplementing and Qi-Boosting Decoction combined with transurethral plasma kinetic enucleation of prostate(PKEP)in the treatment of benign prostatic hyperplasia(BPH)complicated with detrusor underactivity(DU).Methods:A total of 68 patients with BPH combined with DU who underwent PKEP surgery in Fangcun Hospital of Guangdong Provincial Hospital of Chinese Medicine from December 2022 to December 2023 were selected and randomly divided into the control group with 35 cases and the treatment group with 33 cases according to the random number table method.All patients underwent PKEP surgery,and both groups received conventional treatment regimens after surgery.The treatment group was additionally treated with Modified Center-Supplementing and Qi-Boosting Decoction on the basis of conventional treatment.The clinical efficacy,perioperative complications,and changes in IPSS score,IPSS-V score,IPSS-S score,QoL score,post-void residual urine volume(PVR),and maximum urine flow rate(Qmax)before and after treatment were observed in both groups.Results:There were no statistically significant differences between the two groups in terms of the weight of the excised tissue during the operation,the decrease in sodium ions and hemoglobin after the operation,blood loss,hospital stay,and operation time(P>0.05).One month and three months after the operation,the IPSS score,IPSS-V score,IPSS-S score,QoL,PVR and Qmax of both groups were all better than those before the treatment(P<0.05).There were no statistically significant differences in the IPSS score,IPSS-V score,IPSS-S score,QoL and PVR between the two groups one month and three months after the operation(P>0.05).The Qmax of the observation group was lower than that of the control group one month and three months after the operation,and the difference was statistically significant(P<0.05).The effective rate of the treatment group was 78.79%,and that of the control group was 82.86%.There was no statistically significant di

关 键 词：前列腺增生 逼尿肌收缩力低下 补中益气汤加味 等离子前列腺剜除术 

分 类 号：R275.973[医药卫生—中西医结合]