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作 者:赖海丽 徐丹 LAI Haili;XU Dan(Ganzhou Maternity and Child Health Hospital,Ganzhou,Jiangxi,China,341000)
出 处:《河南中医》2025年第3期431-434,共4页Henan Traditional Chinese Medicine
基 金:江西省中医药管理局科技计划项目(2023B1014)。
摘 要:目的:分析妊娠期糖尿病(gestational diabetes mellitus,GDM)患者中医体质类型及与妊娠结局的相关性。方法:回顾性选取2023年6月至2024年6月在赣州市妇幼保健院定点孕期体检的160例孕妇为研究对象,根据是否发生GDM分为GDM组51例和对照组(无妊娠期糖尿病)109例,采用多因素Logistic回归分析GDM患者中医体质与不良妊娠结局的相关性。结果:GDM组不良妊娠结局发生率为31.37%,高于对照组的6.42%,差异有统计学意义(P<0.05)。两组患者年龄、糖尿病家族史、多囊卵巢综合征史、中医体质类型比较,差异有统计学意义(P<0.05)。孕妇年龄较大、有糖尿病家族史、有多囊卵巢综合征史、饮食喜甜食及痰湿质回归系数分别为0.220、1.727、1.952、0.236、4.107,与GDM患者发生不良妊娠结局呈正相关(P<0.05);痰湿质GDM患者发生不良妊娠结局的风险是平和质的60.79倍。结论:孕妇年龄较大、有糖尿病家族史、有多囊卵巢综合征史、饮食喜甜食及痰湿质为孕妇发生不良妊娠结局的独立危险因素;痰湿质人群发生GDM的风险显著高于其他体质类型。Objective:To analyze the TCM constitution types of patients with gestational diabetes mellitus(GDM)and their correlation with pregnancy outcomes.Methods:A retrospective study was conducted on 160 pregnant women who underwent regular prenatal check-ups at Ganzhou Maternity and Child Health Hospital from June 2023 to June 2024.They were divided into the GDM group(51 cases)and the control group(109 cases without pregnancy complications).Multivariate Logistic regression was used to analyze the correlation between TCM constitutions of GDM patients and adverse pregnancy outcomes.Results:The incidence of adverse pregnancy outcomes in the GDM group was 31.37%,which was higher than 6.42%in the control group,and the difference was statistically significant(P<0.05).There were statistically significant differences in age,family history of diabetes,history of polycystic ovary syndrome,and TCM constitution types between the two groups(P<0.05).The regression coefficients of advanced maternal age,family history of diabetes,history of polycystic ovary syndrome,preference for sweet foods in diet and phlegm-dampness constitution were 0.220,1.727,1.952,0.236 and 4.107 respectively,which were positively correlated with adverse pregnancy outcomes in GDM patients(P<0.05);the risk of adverse pregnancy outcomes in GDM patients with phlegm-dampness constitution was 60.79 times greater than that of individuals with a balanced constitution.Conclusion:Advanced maternal age,family history of diabetes,history of polycystic ovary syndrome,preference for sweet foods in diet and phlegm-dampness constitution are independent risk factors for adverse pregnancy outcomes in pregnant women.The risk of GDM in the phlegm-dampness constitution population is significantly higher than that in other constitution types.
分 类 号:R271.914.147[医药卫生—中西医结合]
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