组织内异物声光成像的COMSOL仿真模拟  

COMSOL Simulation of Acousto-Optic Imaging for Foreign Bodies in Tissues

作　　者：覃诗译 张畅 刘遥[1,2,3] 邓辉煌 陈艳 朱莉莉 QIN Shiyi;ZHANG Chang;LIU Yao;DENG Huihuang;CHEN Yan;ZHU Lili(College of Photonic and Electronic Engineering,Fujian Normal University,Fuzhou 350117,China;Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education,Fuzhou 350117,China;Fujian Provincial Key Laboratory of Photonics Technology,Fuzhou 350117,China)

机构地区：[1]福建师范大学光电与信息工程学院,福建福州350117 [2]医学光电科学与技术教育部重点实验室,福建福州350117 [3]福建省光子技术重点实验室,福建福州350117

出　　处：《福建师范大学学报(自然科学版)》2025年第2期117-124,共8页Journal of Fujian Normal University:Natural Science Edition

基　　金：国家自然科学基金青年科学基金项目(11804051);福建省自然科学基金项目(2017J01742、2022J01171)。

摘　　要：采用COMSOL Multiphysics软件对内含异物组织进行声光成像仿真模拟,仿真结果表明:(1)声光信号的峰峰值和调制深度都能对生物组织中的异物进行声光成像,能较准确地再现异物的大小和位置,而声光信号的平均值不能对异物成像;(2)异物的光学参数与周围组织差异越大,成像效果越好;(3)超声焦区越小,声光成像空间分辨率越高,但产生的声光信号较弱,不利于检测,实际应用中需要折中考虑。COMSOL Multiphysics software is used to simulate the acousto-optic imaging of tissues containing foreign bodies.The simulation results show that:(1)The peak-to-peak value and modulation depth of the acousto-optic signal can be used to image foreign bodies in biological tissues and can accurately reproduce their size and position,while the average value of the acousto-optic signal does not effectively contribute to foreign body imaging;(2)The greater the difference between the optical parameters of the foreign body and the surrounding tissue,the better the imaging effect;(3)The smaller the ultrasound focal region,the higher the spatial resolution of acousto-optic imaging,but the resulting acousto-optic signal is weaker,making detection more challenging,which necessitates a trade-off in practical applications.

关 键 词：体内 声光成像 COMSOL Multiphysics 声光信号 异物成像 

分 类 号：Q631[生物学—生物物理学]