从“腠理”理论与“间隙感染学说”的相关性探讨肛瘘的发病机制  

Discussion on pathogenesis of anal fistulae from the correlation between“cou li”theory and“intersphincteric infection theory”

作　　者：陈雪 田瑞 权隆芳[1] 贝绍生 CHEN Xue;TIAN Rui;QUAN Longfang;BEI Shaosheng(Department of Proctology,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing100091,China)

机构地区：[1]中国中医科学院西苑医院肛肠科,北京100091

出　　处：《中国医药导报》2025年第5期154-157,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81373651);中国中医科学院西苑医院提升中医药临床循证证据级别研究专项项目(XYZX0202-01);北京中医药大学教育科学研究课题(XJY23080)。

摘　　要：“间隙感染学说”是当下临床广泛认可的肛瘘发病机制,“腠理”是人体沟通内外的通道,也是外邪侵入的重要门户。本文基于“间隙感染学说”阐述“腠理”理论在肛瘘发病各个环节的作用,提出脾气亏虚、卫不营运、“腠理”不固是肛瘘间隙感染的先决条件,邪舍“腠理”、血气壅结是肛瘘间隙感染的发病基础,正邪交争、阳气逆于“腠理”是肛瘘间隙感染的病理表现,以期为进一步理解肛瘘的病理特点和治疗原则提供思路。“Intersphincteric infection theory”is widely recognized in clinical practice as pathogenesis of anal fistula,“cou li”is a channel for communication between inside and outside of human body,as well as an important gateway for invasion of external pathogens.This article elaborates on the role of“cou li”theory in various stages of anal fistula incidence based on“intersphincteric infection theory”,proposes spleen qi deficiency,ineffective hygiene,and insecurity of“cou li”are prerequisites for anal fistula gap infection,evil sheds“cou li”,blood congestion is basis of the onset of anal fistula infection,conflict between vital qi and pathogen,reversal of yang qi in“cou li”is pathological manifestation of anal fistula infection,in order to provide ideas for further understanding pathological characteristics and treatment principles of anal fistula.

关 键 词：肛瘘 “腠理” “间隙感染学说” 发病机制 

分 类 号：R269[医药卫生—中西医结合]