规律远红外照射对高原红细胞过度增生的干预研究  

Interventional effect of regular far-infrared irradiation on excessive proliferation of red blood cells at high altitudes

作　　者：曹征涛 胡阳 欧阳军 余志祺 邓浩伟 俞梦孙 赵永岐 CAO Zhengtao;HU Yang;OUYANG Jun;YU Zhiqi;DENG Haowei;YU Mengsun;ZHAO Yongqi(Research Department,Air Force Medical Center,Air Force Medical University,PLA,Beijing 100142;Department of Pan Rehabilitation,Sinopharm Gezhouba Central Hospital,Wuhan 430033;Department of Geriatrics,Sinopharm Gezhouba Central Hospital,Wuhan 430033;China Gezhouba Group Co.Ltd,Wuhan 430033;Department of Military Cognition and Stress Medicine,Institute of Military Cognition and Brain Sciences,Academy of Military Medical Sciences,Beijing 100850,China)

机构地区：[1]空军军医大学空军特色医学中心研究部,北京100142 [2]国药葛洲坝中心医院疼痛康复科,武汉430033 [3]国药葛洲坝中心医院老年医学科,武汉430033 [4]葛洲坝集团有限公司,武汉430033 [5]军事医学研究院军事认知与脑科学研究所军事认知与应激医学研究室,北京100850

出　　处：《空军航空医学》2025年第1期24-27,共4页AVIATION MEDICINE OF AIR FORCE

摘　　要：目的针对4000 m以上高原驻留超过1年的健康受试者,采用远红外规律照射,通过红细胞计数的变化考察规律远红外照射对高原红细胞过度增生的干预作用。方法将经过筛选的受试者随机分成远红外干预组(14名)和对照组(25名),排除确诊的慢性高原病患者,远红外干预组接受波长3.5~16.0μm、强度超过200 W的远红外线照射,频率1次/d,持续照射50 d。干预前后采集外周血,检测与高原红细胞增多症密切相关的血红蛋白浓度和红细胞数量,采用自身前后对照和分组对照的方法完成统计分析。结果波长3.5~16.0μm、强度超过200 W的远红外照射对受试没有任何不良影响。干预组可见远红外干预后较干预前收缩压下降、血氧饱和度上升、舒张压和心率下降,差异有统计学意义(Z=-3.184、-2.919,t=3.200、3.983;P<0.001、=0.004、0.007、0.002)。对照组干预后红细胞计数高于干预前(P=0.001)。组间比较结果显示,2组在干预前血红蛋白、红细胞计数、红细胞压积差异均有统计学意义(U=74.000、49.000、79.500,P=0.002、<0.001、=0.004),2组干预后比较差异有统计学意义(H组别=10.010、13.370、9.381,P=0.002、<0.001、0.002)。结论采用远红外全身照射或者局部照射,其高原环境暴露导致的红细胞增加情况得到有效遏制,提示远红外的规律照射能够有效缓解慢性高原相关疾病引起的红细胞过度增长现象,且缓解程度与坚持远红外照射的时长和规律程度有关。Objective To investigate the interventional effect of regular far-infrared irradiation on excessive proliferation of red blood cells at high altitudes via changes in red blood cell counts and regular far infrared irradiation.Methods After rigorous screening,the subjects were randomly divided into the far-infrared intervention group and control group.Patients with chronic high-altitude diseases were excluded.The intervention group received 50 days of farinfrared radiation at the intensity of 200 W once a day.Before and after interventions,peripheral blood was collected and biochemical analysis was conducted.Self-control and intra-group comparison methods were used for statistical analysis.Results Far infrared irradiation at a wavelength of 3.5~16.0μm and an intensity above 200 W had no adverse effects on the subjects.The intervention group showed a significant decrease in systolic blood pressure,but an increase in blood oxygen saturation,diastolic blood pressure,and heart rate(Z=-3.184,-2.919,t=3.200,3.983;P<0.001,=0.004,0.007,0.002).After interventions,the red blood cell count in the control group was increased(P=0.001).The results of intra-group comparison showed that there were statistically significant differences in hemoglobin,red blood cell counts,and HCT between the two groups before interventions(U=74.000,49.000,79.500,P=0.002,<0.001,=0.004)and after interventions(H_(group)=10.010,13.370,9.381,P=0.002,<0.001,0.002).Conclusion Whole-body far-infrared irradiation or local irradiation for more than 30 minutes per day for 50 days can effectively curb the increase in red blood cells caused by high-altitude exposure,suggesting that regular far-infrared radiation can effectively alleviate excessive proliferation of red blood cells caused by chronic diseases related to high altitudes.

关 键 词：高原低氧 慢性损伤 红细胞过度增生 远红外 红细胞计数 

分 类 号：R135.6[医药卫生—劳动卫生]