超早期经颞体表定位双靶点穿刺引流对TH并发脑积水的疗效  

Curative effect of ultra⁃early two⁃target puncture and drainage via temporal body surface for TH⁃complicated hydrocephalus

作　　者：王松 苏菲 周西广 WANG Song;SU Fei;ZHOU Xiguang(Department of Neurosurgery,Xingtai Third People's Hospital,Xingtai,Hebei,China,054000)

机构地区：[1]河北省邢台市第三医院神经外科,河北邢台054000

出　　处：《分子诊断与治疗杂志》2025年第1期112-115,共4页Journal of Molecular Diagnostics and Therapy

基　　金：邢台市科技局项目(2022ZC100)。

摘　　要：目的探讨超早期经颞体表定位双靶点穿刺引流对丘脑出血(TH)并发脑积水的疗效。方法纳入2021年3月至2024年3月间邢台市第三医院神经外科收治的TH并发脑积水患者共120例,根据手术治疗方法分为对照组(45例,常规手术治疗)和研究组(75例,超早期经颞体表定位双靶点穿刺引流术治疗)。比较两组的治疗效果、血清生化指标、术后28天的并发症及预后情况。结果与对照组相比,研究组的血肿清除率较高,脑室引流时间较短(P<0.05);研究组的疗效高于对照组(P<0.05);术后7 d两组的血清碱性磷酸酶(ALP)、同型半胱氨酸(Hcy)和乳酸脱氢酶(LDH)水平均降低,且研究组的均低于对照组(P<0.05);与对照组相比,研究组的颅内感染、分流依赖型脑积水发生率和死亡率均较低,预后良好率较高(P<0.05)。结论超早期经颞体表定位双靶点穿刺术联合脑室穿刺引流术在治疗TH并发脑积水具有确切疗效。Objective To investigate the efficacy of ultra⁃early double⁃target puncture and drainage via temporal surface localization in the treatment of thalamic hemorrhage(TH)complicated with hydrocephalus.Methods A total of 120 patients with TH complicated with hydrocephalus were admitted to the De⁃partment of Neurosurgery,Xingtai Third People's Hospital from March 2021 to March 2024.They divided into two groups based on surgical treatment methods:the control group(45 cases receiving conventional surgical treatment)and the study group(75 cases receiving ultra⁃early double target puncture and drainage through temporal surface positioning).The therapeutic effects,serum biochemical indexes,complications and prognosis 28 days post⁃operation were compared between the two groups.Results Compared to the control group,the study group had a higher hematoma clearance rate and shorter ventricular drainage time(P<0.05).The efficacy of the study group was also superior to that of the control group(P<0.05).The levels of serum alkaline phosphatase(ALP),homocysteine(Hcy),and lactate dehydrogenase(LDH)in both groups decreased 7 days post⁃operation,with the study group showing significantly lower levels compared to the control group(P<0.05).Additionally,the study group had lower incidences of intracranial infection,shunt⁃dependent hydrocephalus,and mortality,along with a higher rate of good prognosis compared to the control group(P<0.05).Conclusion Ultra⁃early double target puncture via temporal surface localization,combined with ventricular puncture and drainage,is effective in the treatment of TH complicated with hydrocephalus.

关 键 词：丘脑出血 脑积水 穿刺引流术 碱性磷酸酶 同型半胱氨酸 乳酸脱氢酶 

分 类 号：R651.1[医药卫生—外科学]