急性有机磷中毒患者病情反跳调查及其影响因素  

Investigation on rebound phenomenon in patients with acute organophosphorus poisoning and its influencing factors

作　　者：谭文慧 叶林红 刘娜 Tan Wenhui;Ye Linhong;Liu Na(Department of Emergency,Lixin People's Hospital,Bozhou 236700,China)

机构地区：[1]利辛县人民医院急诊科,亳州236700

出　　处：《中华保健医学杂志》2025年第1期120-122,共3页Chinese Journal of Health Care and Medicine

基　　金：安徽省卫生健康科研项目(AHWJ2022c042)。

摘　　要：目的调查急性有机磷中毒(AOPP)患者病情反跳情况,并分析其影响因素。方法回顾性选取利辛县人民医院2022年3月~2024年1月期间收治的21例AOPP病情反跳患者为反跳组,同期AOPP病情无反跳的71例患者作为未反跳组。收集受试对象临床资料,并采用单因素及多因素logistic回归分析AOPP患者病情反跳的影响因素。结果单因素及多因素logistic回归分析结果显示,中毒程度(OR=2.284,95%CI=1.104~4.726)、中毒至洗胃时间(OR=2.465,95%CI=1.296~4.687)、急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分(OR=2.158,95%CI=1.132~4.112)均为AOPP患者病情反跳的独立危险因素(P<0.05)。结论AOPP患者病情反跳发生风险较高,中毒程度、中毒至洗胃时间、APACHEⅡ评分是AOPP患者病情反跳的独立危险因素,建议临床救治期间予以重点关注及必要的干预策略。Objective To investigate the rebound phenomenon in patients with acute organophosphorus poisoning(AOPP)and analyze its influencing factors.Methods A retrospective study was conducted.A total of 21 patients with rebound of AOPP(rebound group)and 71 patients without rebound of AOPP(non-rebound group)who were admitted to Lixin People's Hospital from March 2022 to January 2024 were included in the study.Their clinical data were collected,and univariate analysis and multivariate logistic regression analysis were performed to screen the factors influencing rebound of AOPP.Results Univariate analysis and multivariate logistic regression analysis results showed that the degree of poisoning(OR=2.284,95%CI=1.104~4.726),the time from poisoning to gastric lavage(OR=2.465,95%CI=1.296~4.687)and the acute physiology and chronic health evaluationⅡ(APACHⅡ)score(OR=2.158,95%CI=1.132~4.112)were independent risk factors for rebound of AOPP(P<0.05).Conclusion Patients with AOPP have a relatively high risk of rebound.The degree of poisoning,time from poisoning to gastric lavage and APACHEⅡscore are independent risk factors for rebound of AOPP.It is recommended to pay special attention to these factors and necessary intervention strategies should be taken during clinical treatment.

关 键 词：有机磷中毒 急性 病情反跳 影响因素 

分 类 号：R595.4[医药卫生—内科学]