人工尿道括约肌治疗前列腺术后尿失禁的现状和展望  

Current situation and prospects of artificial urethral sphincter in the treatment of postprostatectomy incontinence

作　　者：孙佳寅 卫中庆[1] SUN Jiayin;WEI Zhongqing(Department of Urology,the Second Affiliated Hospital of Nanjing Medical University,Jiangsu Province,Nanjing210011,China)

机构地区：[1]南京医科大学第二附属医院泌尿外科,江苏南京210011

出　　处：《中国医药导报》2025年第6期61-66,共6页China Medical Herald

基　　金：国家自然科学基金资助项目(82370781);江苏省社会发展基金项目(BE2020724)。

摘　　要：手术方案是治疗前列腺术后尿失禁(PPI)的有力武器,人工尿道括约肌(AUS)被认为是PPI的金标准治疗选择。但与其他植入手术相同,AUS植入存在固有的围手术期风险及术后并发症,包括机械性并发症和非机械性并发症。机械性并发症通常涉及装置功能障碍,非机械性并发症包括感染、尿道萎缩、袖套侵蚀等,严重影响患者的生活质量,增加患者的经济负担。因此,了解疾病危险因素及做好并发症处理对治疗至关重要。本文综述PPI的发病机制,总结AUS植入的并发症及处理方法,并对AUS开发的新兴技术和未来治疗方向进行展望。Surgical option is a powerful weapon in the treatment of postprostatectomy incontinence(PPI),and artificial urinary sphincter(AUS)is considered the gold standard treatment option for PPI.But like other implant surgeries,AUS implantation has inherent perioperative risk and postoperative complication,including mechanical complication and non mechanical complication.Mechanical complication usually involves device dysfunction,while non mechanical complication includes infection,urethral atrophy,sleeve erosion,etc.,seriously affecting quality of life of patients,increasing their economic burden.Therefore,understanding risk factors of diseases and managing complications effectively are crucial for treatment.This article reviews the pathogenesis of PPI,summarizes complications and treatment methods of AUS implantation,and looks forward to emerging technologies and future treatment directions of AUS development.

关 键 词：人工尿道括约肌 尿失禁 尿道萎缩 

分 类 号：R694.54[医药卫生—泌尿科学]