宫腔镜下粘连分离术治疗宫腔粘连的临床效果  

Clinical effect of hysteroscopic adhesiolysis of intrauterine adhesion in the treatment of intrauterine adhesion

作　　者：农惠珍 黄梅香 NONG Huizhen;HUANG Meixiang(Department of Gynecology,Wuming Hospital of Guangxi Medical University,Guangxi Zhuang Autonomous Region,Nanning530100,China)

机构地区：[1]广西医科大学附属武鸣医院妇产科,广西南宁530100

出　　处：《中国当代医药》2025年第6期87-90,共4页China Modern Medicine

摘　　要：目的评估宫腔镜下粘连分离术应用在宫腔粘连(IUA)患者中的临床效果。方法选取2021年6月至2023年6月广西医科大学附属武鸣医院收治的80例IUA患者作为研究对象,按照随机数表法分为对照组(40例)与观察组(40例)。对照组采用宫腔镜下电切术,观察组采用宫腔镜下冷刀分离术。比较两组患者的临床有效率、子宫恢复情况、宫腔再粘连率、临床指标、炎症因子[白介素-10(IL-10)、白介素-4(IL-4)、白介素-6(IL-6)]。结果观察组临床有效率和IL-10、IL-4水平高于对照组,差异有统计学意义(P<0.05);观察组宫腔再粘连率、IL-6水平低于对照组,差异有统计学意义(P<0.05);观察组手术时间、住院时间短于对照组,差异有统计学意义(P<0.05);观察组膨宫液吸收量、术中出血量少于对照组,差异有统计学意义(P<0.05);观察组子宫内膜厚度厚于对照组,差异有统计学意义(P<0.05);观察组子宫体积大于对照组,差异有统计学意义(P<0.05)。结论较之宫腔镜下电切术,对IUA患者实施宫腔镜下冷刀分离术更能提高临床有效率,促进子宫恢复,降低宫腔再粘连率,优化临床指标,减轻炎症反应。Objective To evaluate the clinical effect of hysteroscopic adhesiolysis of intrauterine adhesion in patients with intrauterine adhesion(IUA).Methods A total of 80 patients with IUA admitted to Wuming Hospital of Guangxi Medical University from June 2021 to June 2023 were selected as research objects and they were divided into control group(40 cases)and observation group(40 cases)according to random number table method.The control group underwent hysteroscopic electric resection,and the observation group underwent hysteroscopic cold knife separation.The clinical effective rate,uterine recovery,uterine readhesion rate,clinical indicators and inflammatory factors(interleukin-10[IL-10],interleukin-4[IL-4],interleukin-6[IL-6])of the two groups were compared.Results The clinical effective rate and the levels of IL-10 and IL-4 in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).The intrauterine readhesion rate and IL-6 level in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The operation time and hospital stay in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).The amount of dilatant fluid absorption and intraoperative blood loss in the observation group were lower than those in the control group,and the difference were statistically significant(P<0.05).The endometrial thickness in the observation group was thicker than that in the control group,and the difference was statistically significant(P<0.05).The uterine volume of observation group was higher than that of control group,and the difference was statistically significant(P<0.05).Conclusion Compared with hysteroscopic electrotomy,hysteroscopic cold knife separation can improve clinical efficiency,promote uterine recovery,reduce uterine readhesion rate,optimize clinical indicators,and alleviate inflammation in IUA patients.

关 键 词：宫腔镜下粘连分离术 宫腔粘连 临床效果 炎症因子 子宫恢复情况 

分 类 号：R713[医药卫生—妇产科学]