瑞马唑仑与丙泊酚在妇科腹腔镜术中麻醉效果的比较  

Comparison of the anesthetic effect of Remimazolam and Propofol in gynecological laparoscopic surgery

作　　者：张宝华 杨帆[1] 周倩倩 ZHANG Baohua;YANG Fan;ZHOU Qianqian(Department of Anesthesiology,Jiujiang Maternal and Child Health Hospital,Jiangxi Province,Jiujiang332000,China)

机构地区：[1]江西省九江市妇幼保健院麻醉科,江西九江332000

出　　处：《中国当代医药》2025年第6期102-105,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202120062);江西省九江市科技计划项目(S2023ZDYFN541)。

摘　　要：目的探究腹横肌平面阻滞(TAPB)分别联合瑞马唑仑与丙泊酚在妇科腹腔镜术中的应用效果。方法选取2023年1月至2024年4月九江市妇幼保健院收治的74例行腹腔镜手术患者作为研究对象,按照随机数字表法将其分为试验组(37例)与对照组(37例)。所有患者均行TAPB手术,试验组联合苯磺酸瑞马唑仑,对照组联合丙泊酚。比较两组患者不同时间点生命体征指标[心率(HR)、脑电双频指数(BIS)、平均动脉压(MAP)]水平、麻醉苏醒情况、术后疼痛评分(VAS)、不良反应。结果两组患者不同时间点HR、MAP、BIS指标水平比较,差异均无统计学意义(P>0.05)。试验组麻醉苏醒时间短于对照组,差异有统计学意义(P<0.05)。试验组术后2、12 h的VAS评分低于对照组,差异有统计学意义(P<0.05)。试验组的不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论与丙泊酚相比,TAPB联合瑞马唑仑在妇科腹腔镜手术应用中获得较好的麻醉效果,患者围手术期生命体征水平较为稳定,麻醉苏醒时间较短,疼痛感较轻,且术后并发症发生率较低,安全可靠,值得推广应用。Objective To investigate the application effect of transverse abdominis plane block(TAPB)combined with Remimazolam and Propofol in gynecological laparoscopic surgery.Methods Seventy-four patients undergoing laparoscopic surgery admitted to Jiujiang Maternal and Child Health Hospital from January 2023 to April 2024 were selected as the study objects,and they were divided into experimental group(37 cases)and control group(37 cases)according to random number table method.All patients underwent TAPB surgery,with the experimental group receiving a combination of Remimazolam Besylate and the control group receiving a combination of Propofol.The levels of vital signs(heart rate[HR],bispecific index[BIS],mean arterial pressure[MAP]),anesthesia recovery status,postoperative pain score(VAS),and adverse reactions between two groups of patients at different time points were compared.Results There were no significant differences in HR,MAP and BIS indexes between the two groups at different time points(P>0.05).The anesthesia recovery time of experimental group was shorter than that of control group,and the difference was statistically significant(P<0.05).VAS scores of experimental group at 2 and 12 h after operation were lower than those of control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in experimental group was lower than that in control group,the difference was statistically significant(P<0.05).Conclusion Compared with Propofol,TAPB combined with Remimazolam achieves better anesthesia effect in gynecological laparoscopic surgery.The patient's perioperative vital signs are relatively stable,the anesthesia recovery time is shorter,the pain is lighter,and the incidence of postoperative complications is lower.It is safe and reliable,and worthy of promotion and application.

关 键 词：妇科腹腔镜手术 腹横肌平面阻滞 丙泊酚 瑞马唑仑 

分 类 号：R614[医药卫生—麻醉学]