六味地黄汤合五味消毒饮加减促进肛周脓肿合并糖尿病患者术后创面愈合效果观察  

Effect of Liuwei Dihuang decoction with modified Wuwei Xiaodu drink on promoting wound healing after perianal abscess surgery in diabetic patients

作　　者：史瑞霞 许丽萍 华浩 耿俊 SHI Ruixia;XU Liping;HUA Hao(Proctology of Traditional Chinese and Western Medicine of Wuxi Xishan People's Hospital,Jiangsu,Wuxi 214105,China;Department of Endocrinology of Wuxi Xishan People's Hospital,Jiangsu,Wuxi 214105,China)

机构地区：[1]无锡市锡山人民医院中西医结合肛肠科,江苏无锡214105 [2]无锡市锡山人民医院内分泌科,江苏无锡214105

出　　处：《四川中医》2025年第2期160-163,共4页Journal of Sichuan of Traditional Chinese Medicine

基　　金：无锡市中医药管理局科技项目(编号:ZYKJ202019)。

摘　　要：目的:探究六味地黄汤合五味消毒饮加减促进肛周脓肿合并糖尿病患者术后创面愈合效果。方法:按简单随机化分组法将2021.8~2023.8期间我院就诊的阴虚火旺证肛周脓肿合并糖尿病患者分为观察组和对照组,各35例。两组均接受肛周脓肿根治术,术后对照组接受常规西医治疗;观察组在对照组基础上接受六味地黄汤合五味消毒饮加减治疗。比较两组患者治疗期间创面愈合情况(腐肉脱落时间、上皮新生时间、创口愈合时间),以及比较治疗前和治疗1个月后的中医证状积分、血糖水平和炎症水平,并比较治疗1个月期间的不良反应。结果:治疗期间,观察组的腐肉脱落时间、上皮新生时间、创口愈合时间均短于对照组(P<0.05)。治疗1个月后,两组患者的中医证状积分、血糖水平和炎症水平较治疗前显著降低,且观察组低于对照组(P<0.05)。治疗期间,两组不良反应发生率差异不显著(P>0.05)。结论:六味地黄汤合五味消毒饮加减促进肛周脓肿合并糖尿病患者术后创面愈合,显著改善患者血糖水平和炎症水平。Objective:To explore the effect of Liuwei Dihuang decoction with modified Wuwei Xiaodu drink on the promotion of wound healing after perianal abscess surgery in patients with diabetes mellitus.Methods:According to the simple randomization grouping method,patients with diabetes mellitus complicated with perianal abscess with yin deficiency and fire excess syndrome in our hospital from August 2021to August 2023were divided into observation group(35cases)and control group(35cases).Both groups received radical resection of perianal abscess,and the control group received routine western medicine treatment after surgery while the observation group was treated with Liuwei Dihuang decoction with modified Wuwei Xiaodu drink on the basis of the control group.The wound healing status(carrion shedding time,epithelial regeneration time,wound healing time),TCM syndromes scores,blood glucose and inflammation level before treatment and after 1month of treatment and adverse reactions during 1month of treatment were compared.Results:During treatment,the carrion shedding time,epithelial regeneration time and wound healing time in observation group were shorter than those in control group(P<0.05).The TCM symptoms scores,blood glucose indicators and inflammation level in both groups were significantly reduced after 1month of treatment than those before treatment,and the scores and levels in observation group were lower compared to control group(P<0.05).There were no obvious differences in the incidence rates of adverse reactions between groups during treatment(P>0.05).Conclusion:Liuwei Dihuang decoction with modified Wuwei Xiaodu drink can promote wound healing after perianal abscess surgery,and significantly improve blood glucose and inflammation level in patients with diabetes mellitus.

关 键 词：六味地黄汤 五味消毒饮加减 糖尿病 肛周脓肿术 创面愈合 

分 类 号：R266[医药卫生—中医外科学]