芩连平胃散加减联合盐酸多西环素治疗玫瑰痤疮(肺胃蕴热型)美容效果分析  

Cosmetic effect of modified Qinlian Pingwei Powder combined with doxycycline hydrochloride on rosacea(lungstomach accumulating heat type)

作　　者：刘芳 张德爱[1] 顾瑞 LIU Fang;ZHANG De Ai;GU Rui(Lu'an Traditional Chinese Medicine Hospital Dermatology Department,Anhui,Lu'an 237000,China)

机构地区：[1]六安市中医院皮肤科,安徽六安237000

出　　处：《四川中医》2025年第2期172-175,共4页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:探究芩连平胃散加减联合盐酸多西环素治疗玫瑰痤疮(肺胃蕴热型)美容效果。方法:研究对象为60例玫瑰痤疮患者,均在我院进行治疗,入院时间为2021年1月~2023年9月。采用随机数字表法分为对照组30例行盐酸多西环素口服治疗,观察组30例在其基础上行芩连平胃散加减治疗。8周后,对比两组临床疗效,观察两组治疗前后皮损程度,面部美观度[临床医师红斑评估量表(CEA)、温哥华瘢痕量表(VSS)、面部纹理值],查看不良反应发生情况、随访6个月后复发情况。结果:经8周治疗,观察组治疗有效率93.33%高于对照组63.33%(P<0.05);两组红斑、毛细血管扩张、丘疹脓疱等皮疹评分均较治疗前降低,且观察组降低较多(P<0.05);两组CEA评分、VSS评分以及面部纹理值较治疗前降低,且观察组降低较多(P<0.05);观察组不良反应率与6个月后复发率低于对照组(P<0.05)。结论:芩连平胃散加减联合盐酸多西环素治疗玫瑰痤疮能够有效缓解患者皮损程度,改善面部美观度,疗效显著,且复发率低。Objective:To explore the cosmetic effect of modified Qinlian Pingwei Powder combined with doxycycline hydrochloride on rosacea(lung-stomach accumulating heat type).Methods:A total of 60patients with rosacea treated in the hospital were enrolled as the research objects between January 2021and September 2023.According to random number table method,they were divided into control group(30cases,oral doxycycline hydrochloride)and observation group(30cases,modified Qinlian Pingwei Powder combined with doxycycline hydrochloride).After 8weeks of treatment,clinical curative effect in the two groups was compared.The severity of facial aesthetics[clinician erythema assessment scale(CEA),vancouver scar scale(VSS),facial texture]in the two groups were observed before and after treatment.The occurrence of adverse reactions was examined,and recurrence was followed up after 6months of treatment.Results:The response rate of treatment was higher in observation group than control group after treatments of 8weeks(93.33%vs 63.33%,P<0.05).After treatment,scores of rash(erythema,telangiectasia,papulopustule)were decreased in both groups,which were lower in observation group(P<0.05).After treatment,CEA score,VSS score and facial texture were decreased in both groups,which were lower in observation group(P<0.05).The adverse reaction rate and recurrence rate after 6months were lower in observation group than control group(P<0.05).Conclusion:Modified Qinlian Pingwei Powder combined with doxycycline hydrochloride can effectively improve facial aesthetics in rosacea patients,with significant curative effect and low recurrence rate.

关 键 词：玫瑰痤疮 芩连平胃散加减 盐酸多西环素 美容 

分 类 号：R275.9[医药卫生—中西医结合]