中医经典方剂干预新冠病毒感染多系统后遗症的述评  

Classical Formulas of Traditional Chinese Medicine in the Treatment of Multi-System Sequelae of Novel Coronavirus Infection:A Review

作　　者：袁欣 邹璐[1] 杨爱东[1,2] YUAN Xin;ZOU Lu;YANG Aidong(School of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Chinese Medicine Epidemic Research Center,Shanghai Institute of Infectious Diseases and Biosecurity,Shanghai 200032,China)

机构地区：[1]上海中医药大学中医学院,上海201203 [2]上海市重大传染病和生物安全研究院中医药疫病研究中心,上海200032

出　　处：《广州中医药大学学报》2025年第3期789-796,共8页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:82104708);上海市市级科技重大专项(编号:ZD2021CY001,ZXS004R4-1)。

摘　　要：经有效治疗后,新型冠状病毒感染(简称新冠病毒感染)患者可进入康复期,但康复期患者仍可能遭受多系统后遗症。现代医学对于新冠病毒感染多系统后遗症的治疗主要采用对症治疗,尚无特效治疗方法。中医认为,新冠病毒感染可归属“湿毒疫”“寒湿疫”。新冠病毒感染后因余邪未清,反复煎灼阴液,易使患者真阴耗伤,产生多系统损伤。中医经典方剂组方精良,且已经过长时间的临床验证,疗效确切。本文综述了有关中医经典方剂干预新冠病毒感染后遗症的文献,认为新冠病毒感染后累及呼吸系统易造成慢性咳嗽、肺纤维化、呼吸困难等,可分别选用小青龙汤、小柴胡汤,麦门冬汤、补阳还五汤、补肺汤,千金苇茎汤等加减治疗;累及消化系统易致腹痛与腹泻、食欲不振等,可分别选用柴胡桂枝干姜汤、小柴胡汤,补中益气汤、益胃汤等加减治疗;累及神经系统可致神经性头痛、睡眠障碍、认知功能障碍等,可分别选用桂枝汤合川芎茶调散、当归四逆汤、麻黄汤、桂枝汤、葛根汤、吴茱萸汤、麻黄附子细辛汤、理中丸,酸枣仁汤、四逆加柴桂龙骨牡蛎汤,人参养荣汤、菖蒲郁金汤合抵当汤等加减治疗;累及循环系统易致胸闷与胸痛、心悸,可分别选用温胆汤合丹参饮及桃红四物汤、参附汤合桂枝甘草龙骨牡蛎汤,桂枝汤合炙甘草汤及生脉饮、生脉饮合升陷汤、黄芪生脉饮合三甲复脉汤、李氏清暑益气汤合薛氏五叶芦根汤、桃红四物汤合血府逐瘀汤等加减治疗。从中医经典方剂中寻找治疗新冠病毒感染后遗症的有效药物,可为新冠病毒感染后的多系统后遗症的治疗提供参考。Patients with novel coronavirus pneumonia enter the recovery period after effective intervention,but the patients in the recovery period may then suffer from multi-system sequelae.Symptomatic treatment is considered as the primary method for the treatment of multi-system sequelae of novel coronavirus infection in modern medicine,and there are no specific effective therapies yet.In the view of traditional Chinese medicine(TCM),novel coronavirus pneumonia can be categorized as damp-toxin pestilence and cold-damp pestilence,and the multi-system sequelae of novel coronavirus pneumonia result from the lingering pathogens,which consume the yin fluid continuously and lead to the injury of kidney yin.Classical formulas of TCM are formulated excellently and exert definite efficacy which have been confirmed by long-term clinical experience.This paper reviewed the literature on the classical formulas of TCM in the treatment of sequelae of novel coronavirus pneumonia.It is concluded that chronic cough,pulmonary fibrosis,dyspnea are the common respiratory disorders associated with novel coronavirus pneumonia,and can be treated separately by Xiao Qinglong Decoction and Xiao Chaihu Decoction,by Maimendong Decoction,Buyang Huanwu Decoction and Bufei Decoction,and by Qianjin Weijing Decoction for modification.Abdominal pain and diarrhea,and poor appetite are the common digestive disorders associated with novel coronavirus pneumonia,and can be treated separately by Chaihu Guizhi Ganjiang Decoction and Xiao Chaihu Decoction,and by Buzhong Yiqi Decoction and Yiwei Decoction for modification.Neurological headache,sleep disorders,and cognitive dysfunction are the common neurological disorders associated with novel coronavirus pneumonia,and can be treated separately by Guizhi Decoction plus Chuanxiong Cha Tiao Powder,Danggui Sini Decoction,Mahuang Decoction,Guizhi Decoction,Gegen Decoction,Wuzhuyu Decoction,Mahuang Fuzi Xixin Decoction and Lizhong Pills,by Suanzaoren Decoction and Sini Decoction plus Chai Gui Longgu Muli Decoction,and

关 键 词：新冠病毒感染后遗症 中医经典方 恢复期治疗 慢性咳嗽 肺纤维化 呼吸困难 小青龙汤 小柴胡汤 

分 类 号：R259.631[医药卫生—中西医结合]