TEAS预处理对全身麻醉阑尾切除术舒芬太尼诱发咳嗽的抑制作用及早期恢复质量的影响  

The inhibitory effect of TEAS pretreatment on cough induced by sufentanil during appendectomy under general anesthesia and its impact on early recovery quality

作　　者：纪腾飞 邱永芳 杨璟辉 陈国旺 JI Tengfei;QIU Yongfang;YANG Jinghui;CHEN Guowang(Department of Anesthesiology,Jinjiang Hospital of Traditional Chinese Medicine,Fujian,Jinjiang 362200,China;Operation Room,Jinjiang Hospital of Traditional Chinese Medicine,Fujian,Jinjiang 362200,China;Department of Rehabilitation,Jinjiang Hospital of Traditional Chinese Medicine,Fujian,Jinjiang 362200,China)

机构地区：[1]福建省晋江市中医院麻醉科,福建晋江362200 [2]福建省晋江市中医院手术室,福建晋江362200 [3]福建省晋江市中医院康复科,福建晋江362200

出　　处：《中国医药科学》2025年第4期66-71,共6页China Medicine And Pharmacy

基　　金：福建中医药大学校管科研课题项目(XB2021078)。

摘　　要：目的探讨经皮穴位电刺激(TEAS)预处理对舒芬太尼诱发咳嗽的抑制作用及对全身麻醉阑尾切除术后早期恢复质量的影响。方法回顾性分析2022年1月至2023年1月在晋江市中医院实施全身麻醉下腹腔镜阑尾切除术的100例患者资料。根据有无进行TEAS预处理,将患者分为观察组和对照组,每组各50例。观察组在麻醉诱导前30 min接受TEAS预处理,对照组则未接受电刺激治疗。记录并分析两组患者的咳嗽发生率、术后苏醒时间、拔管时间、疼痛视觉模拟评分法(VAS)评分、生命体征、不良事件、C反应蛋白(CRP)、白细胞介素-6(IL-6)及匹兹堡睡眠质量指数(PSQI)评分。结果观察组的咳嗽发生率显著低于对照组(P<0.05),术后苏醒时间和拔管时间短于对照组(P<0.05)。观察组出恢复室时和术后6 h的VAS评分均低于对照组(P<0.05)。观察组舒芬太尼静推后1 min(T2)的心率(HR)和平均动脉血压(MAP)均低于对照组(P<0.05)。观察组的不良事件总发生率低于对照组(P<0.05),其中恶心呕吐的发生率差异有统计学意义(P<0.05)。观察组入恢复室时和术后1 d的CRP和IL-6水平均低于对照组(P<0.05)。观察组术后24 h的PSQI评分低于对照组(P<0.05)。结论TEAS预处理能有效抑制舒芬太尼诱发的咳嗽,提高全身麻醉阑尾切除术后患者的早期恢复质量,减轻术后疼痛和炎症反应,改善睡眠质量。Objective To investigate the inhibitory effect of transcutaneous electrical acupoint stimulation(TEAS)pretreatment on cough induced by sufentanil and its impact on the early recovery quality after appendectomy under general anesthesia.Methods The data of 100 pa tients who underwent general anesthesia laparoscopic appendectomy admitted to Jinjiang Hospital of Traditional Chinese Medicine from January 2022 to January 2023 were analyzed retrospectively.According to the presence or absence of TEAS pretreatment,patients were divided into the observation group(n=50)and the control group(n=50).The observation group was treated with TEAS pretreatment 30 minutes before anesthesia induction.The control group was not treated with electricals timulation therapy.T he cough incidence,pos toperative recovery tim e,extubation time,visual analogue score(VAS)scores,vital signs,adverse events,C-reactive protein(CRP),interleukin-6(IL-6),and Pittsburgh sleep quality index(PSQI)scores of two groups of patients were recorded and analyzed.Results The incidence of cough in the observation group was significantly lower than that in the control group(P<0.05),and the postoperative awakening time and extubation time were shorter than that in the control group(P<0.05).The VAS scores of the observation group at the time of leaving the recovery room and at 6 h postoperatively were lower than those of the control group(P<0.05).T he heart rate(HR)and mean artery pressure(MAP)at 1 min after sufentanil sedation(T2)were lower in the observation group than in the control group(P<0.05).The total incidence of adverse events in the observation group was lower than that in the control group(P<0.05),of which the difference in the incidence of nausea and vomiting was statistically significant(P<0.05).The CRP and IL-6 levels in the observation group were lower than those in the control group at the time of admission to the recovery room and 1 d postoperatively(P<0.05).The PSQI score of the observation group was lower than that of the control group at 24 h p

关 键 词：经皮穴位电刺激 舒芬太尼 咳嗽 全身麻醉 阑尾切除术 早期恢复质量 

分 类 号：R614[医药卫生—麻醉学] R246.2[医药卫生—外科学]