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作 者:付伟 熊斌 廖巧聪 詹华玉 FU Wei;XIONG Bin;LIAO Qiaocong;ZHAN Huayu(Department of Oncology,907th Hospital of PLA Joint Logistic Support Force,Fujian,Nanping 353000,China)
机构地区:[1]解放军联勤保障部队第九〇七医院肿瘤科,福建南平353000
出 处:《中国医药科学》2025年第4期102-105,共4页China Medicine And Pharmacy
基 金:福建中医药大学校管科研课题(XB2023216)。
摘 要:目的研究经皮穴位电刺激对胃癌患者术后全身炎症反应综合征发生率的影响。方法选取2019年1月至2023年1月解放军联勤保障部队第九〇七医院诊治的80例胃癌并且进行手术治疗的患者作为对象,采取随机数表法分为两组,每组各40例。对照组应用假经皮穴位电刺激进行治疗,观察组应用经皮穴位电刺激进行治疗。比较两组患者的临床效果、治疗前后炎症反应、全身炎症反应综合征发生率以及胃肠功能。结果观察组的治疗总有效率为95.00%,高于对照组的77.50%,差异有统计学意义(P<0.05)。治疗后,观察组和对照组白细胞介素(IL)-2、IL-10、IL-6水平均高于治疗前,与对照组相比,观察组各项指标水平更高,差异有统计学意义(P<0.05)。观察组与对照组全身炎症反应综合征发生率比较,差异有统计学意义(P<0.05)。观察组和对照组食管下括肌长度、食管收缩幅度、食管蠕动波传导速度治疗后高于治疗前,食管下括约肌压力低于治疗前,且观察组食管动力指标优于对照组,差异有统计学意义(P<0.05)。结论胃癌患者术后采取经皮穴位电刺激治疗后,可有效减轻患者术后炎症反应,改善免疫抑制,临床应用价值较高。Objective To investigate the effect of percutaneous acupoint electrical stimulation on the incidence of postoperative systemic inflammatory response syndrome in patients with gastric cancer.Methods A total of 80 patients with gastric cancer diagnosed and treated by 907th Hospital of PLA Joint Logistic Support Force from January 2019 to January 2023 who underwent surgical treatment were selected as subjects for study,and were divided into two groups with 40 cases each by random number table method.The control group was treated with pseudo-percutaneous acupoint electrical stimulation,and the observation group was treated with percutaneous acupoint electrical stimulation.The clinical effect,inflammatory response before and after treatment,incidence of systemic inflammatory response syndrome and gastrointestinal function of the two groups were compared.Results The total effective rate of the observation group was 95.00%,higher than that of the control group was 77.50%,the difference was statistically significant(P<0.05).After treatment,the levels of interleukin(IL)-2,IL-10 and IL-6 in the observation group and the control group were higher than those before surgery,and the water level of each index in the observation group was higher than that in the control group,with statistical significance(P<0.05).The incidence of systemic inflammatory response syndrome between the observation group and the control group was statistically significant(P<0.05).The length of lower esophageal sphincter muscle,esophageal contraction amplitude and esophageal peristaltic wave conduction velocity of the observation group and the control group were higher after treatment than before treatment,and the lower esophageal sphincter pressure was lower than before treatment,and the esophageal dynamic index of the observation group was better than that of the control group,with statistical significance(P<0.05).Conclusion Percutaneous acupoint electrical stimulation can effectively reduce postoperative inflammatory response and improve immunosuppr
关 键 词:胃癌术后 经皮穴位电刺激 全身炎症反应综合征 临床效果
分 类 号:R246.5[医药卫生—针灸推拿学]
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