脂肪因子在子宫内膜异位症中的研究进展  

Research progress of adipokines in endometriosis

作　　者：乔慧慧 李小丽[2] QIAO Huihui;LI Xiaoli(Second Clinical College of Shanxi Medical University,Taiyuan,Shanxi 030001,China;Department of Gynecology,Shanxi Maternal and Child Health Hospital,Shanxi Maternity Hospital,Taiyuan,Shanxi 030001,China)

机构地区：[1]山西医科大学第二临床医学院,山西太原030001 [2]山西省妇幼保健院、山西省妇产医院妇科,山西太原030001

出　　处：《安徽医药》2025年第4期666-671,共6页Anhui Medical and Pharmaceutical Journal

基　　金：山西省妇幼保健院院内项目(2022037)。

摘　　要：子宫内膜异位症是一种常见的妇科疾病,其发病机制尚不完全清楚。近年来研究表明,脂联素、瘦素、抵抗素等多种激素类脂肪因子可能通过调节细胞凋亡、增殖和迁移能力,改变机体炎症反应和血管生成等多种途径,干扰子宫内膜细胞的正常功能,最终导致异位病变的形成与发展。因此,该研究就脂肪因子在子宫内膜异位症发生发展中的研究进展进行综述,深入探索脂肪因子与子宫内膜异位症发病机制的关系,为疾病的诊断和治疗提供新的靶点和策略。Endometriosis is a common gynecological disease,but its pathogenesis is not fully understood.Recent studies have shown that adipokines may play an important role in the occurrence and development of endometriosis.Adiponectin,leptin,resistin and other hormonal adipokines may interfere with the normal function of endometrial cells by regulating cell apoptosis,proliferation and migra-tion,changing the inflammatory response and angiogenesis of the body,and eventually lead to the formation and development of ectopic lesions.Therefore,this study reviews the research progress of adipokines in the occurrence and development of endometriosis,explores the relationship between adipokines and the pathogenesis of endometriosis,and provides new targets and strategies for the diagnosis and treatment of the disease.

关 键 词：脂肪因子 子宫内膜异位症 炎症 血管生成 免疫 

分 类 号：R71[医药卫生—妇产科学]