温胆汤及其加减方治疗代谢相关性疾病的研究进展  

Research progress in the treatment of metabolic related diseases with Wendan fidecoction and its modified formulas

作　　者：袁雅丹 蒋淑君 张彦亮 YUAN Yadan;JIANG Shujun;ZHANG Yanliang(Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210001,China)

机构地区：[1]南京中医药大学附属南京市中医院,南京210001

出　　处：《长春中医药大学学报》2025年第3期328-333,共6页Journal of Changchun University of Chinese Medicine

基　　金：江苏省卫生健康委科研课题(2020033)。

摘　　要：温胆汤最早出自南北朝名医姚僧垣所撰写的《集验方》,被孙思邈收录引用至《千金要方》中。温胆汤主要用于治疗胆郁痰扰证,其祛痰效果显著,因此在中医领域被誉为祛痰的名方。随着现代研究的不断深入,温胆汤的临床应用范围实际上远超传统认知,尤其是在代谢相关性疾病的治疗中,温胆汤展现出了其独特且多靶点药用特色。结合近年相关文献,从肥胖、脂肪性肝病、高脂血症、糖尿病、痛风等疾病入手,总结了温胆汤及其加减方治疗代谢性疾病的作用靶标及临床适应证,从而得以推动科研与临床的进一步发展,为温胆汤(加减)在代谢相关性疾病的临床运用提供参考依据。Wen Dan decoction was originally written by the famous physician Yao Sengyuan in the Southern and Northern Dynasties in his book"Ji Yan Fang",and was included and quoted by Sun Simiao in his book"Qian Jin Yao Fang".Wendan decoction is mainly used to treat disturbagallbladder depression and phlegm nce syndrome,and its expectorant effect is significant,so it is known as a famous formula for expectorant treatment in the field of traditional Chinese medicine.With the continuous deepening of modern research,the clinical application scope of Wendan decoction is actually far beyond traditional knowledge,especially in the treatment of metabolic related diseases.Wendan decoction has demonstrated its unique and multi-target medicinal characteristics.Combined with relevant literature in recent years,starting with obesity,fatty liver disease,hyperlipidemia,diabetes,gout and other diseases,this paper summarizes the targets and clinical indications of Wendan decoction and its modified prescriptions for the treatment of metabolic diseases,so as to promote the further development of scientific research and clinic,and provide reference for the clinical application of Wendan decoction(modified)in metabolic related diseases.

关 键 词：温胆汤 代谢相关性疾病 研究进展 

分 类 号：R259[医药卫生—中西医结合]