中医药治疗痰浊阻肺型AECOPD疗效及对气道黏液相关性的研究进展  

Research progress in the therapeutic efficacy of traditional Chinese medicine in treating AECOPD with phlegm turbidity obstruction and its correlation with airway mucus

作　　者：张粟宁 赵榕 田小亚 牛彩琴[1] ZHANG Suning;ZHAO Rong;TIAN Xiaoya;NIU Caiqin(The Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]川北医学院附属医院,四川南充637000

出　　处：《长春中医药大学学报》2025年第3期339-343,共5页Journal of Changchun University of Chinese Medicine

基　　金：四川省中医药管理局面上项目(2023MS340);四川省南充市校合作项目(22SXQT0150)。

摘　　要：慢性阻塞性肺疾病(COPD)是常见、多发、易反复的呼吸系统疾病。气道慢性炎症和黏液高分泌是慢阻肺的主要病理特征,西医治疗和预防COPD病情反复甚至加重方面疗效有限。中医认为伏痰内蕴是慢阻肺的发病基础,中医药在治疗COPD气道慢性炎症及黏液高分泌状态优势明显,能通过多靶点、多途径减轻COPD患者气道慢性炎症和调节气道粘液分泌。通过近5年中医药治疗痰浊阻肺型AECOPD的文献资料,分析了中医药治疗痰浊阻肺型AECOPD的疗效及对气道黏液高分泌的影响,以期为慢阻肺的治疗开拓新思路,并进一步为临床研究提供理论指导。Chronic obstructive pulmonary disease(COPD)is a common,multiple,and easily recurrent respiratory system disease.Chronic inflammation of the airways and high secretion of mucus are the main pathological features of COPD,and the efficacy of Western medicine in treating and preventing the recurrence or even exacerbation of COPD is limited.Traditional Chinese medicine believes that the accumulation of phlegm is the basis of COPD.Traditional Chinese medicine has the significant advantages in treating chronic inflammation and high secretion of mucus in the airways of COPD patients,and can alleviate COPD patients'chronic inflammation and regulate airway mucus secretion through multiple targets and pathways.This study analyzes the therapeutic effect of traditional Chinese medicine on phlegm obstructed lung type AECOPD and its impact on airway mucus hypersensitivity through literature review in the past 5 years,in order to explore new ideas for the treatment of COPD and provide theoretical guidance for clinical research.

关 键 词：中医药 痰浊阻肺型 慢性阻塞性肺疾病急性加重期 疗效 气道黏液 

分 类 号：R259[医药卫生—中西医结合]