Application Research of Acute Skin Injury Model in Soothing Efficacy Evaluation  

作　　者：Li Jing Wu Mingcheng Wu Lishi Shi Xuedong Zhou Panfeng He Jitian 

机构地区：[1]Guangzhou Tianxi Biotechnology Co.,Ltd.,China

出　　处：《China Detergent & Cosmetics》2025年第1期22-26,共5页日用化学品科学(英文版)

摘　　要：An acute skin injury model using continuous tape tearing was established,and studies the application of this model in the evaluation of soothing effects through instrument evaluation.30 healthy adult subjects were selected as the research subjects,and an acute skin model was established on the forearm flexion side of the subjects.The skin color a^(*)value and transdermal water loss rate(TEWL)value of the blank and experimental groups were tested using instruments.The results showed that at 15 and 30 minutes after using the sample,the growth values of a^(*)value and TEWL value in the experimental group were significantly lower than those in the blank group(P<0.05),the acute skin lesion model can effectively evaluate the soothing effect of cosmetics.

关 键 词：soothing MODEL efficacy evaluation COSMETIC 

分 类 号：R75[医药卫生—皮肤病学与性病学]