Effects of Chamomilla Recutita Extract on Soothing Adult Acne Sequelae  

作　　者：Xu Qingyang Jiang Yueming Lu Wenjia 

机构地区：[1]Shanghai Innovation Technical Center,Ashland(China)Holdings Co.,Ltd.,China

出　　处：《China Detergent & Cosmetics》2025年第1期27-34,共8页日用化学品科学(英文版)

摘　　要：Cutibacterium acnes were used to induce lipase production,and to establish ex-vivo skin model of inflammatory response and post-inflammatory hyperpigmentation,in purpose of exploring the mechanism of chamomilla recutita extract.Clinical study was designed to investigate the effects of chamomilla recutita extract on Chinese volunteers with sequelae of adult acne,by evaluating the severity of acne,post-acne erythema and pigmentation,skin basic physiological conditions.The results showed that chamomilla recutita extract inhibited lipase activity,cellular inflammatory response,and melanin production.In the clinical study,the acnes were relieved 173%,with a 78%lower post-acne erythema index and 202%less hyperpigmentation as compared to placebo,after applying samples containing 1%chamomilla recutita extract for 28 days.Meanwhile,chamomilla recutita extract showed instant oil control effect.The extract significantly reduced sebum secretion by 293%,increased skin moisture content by 102%,and strengthened the skin barrier by 193%after 28 days application,which provided favorable skin physiological basis for the prevention and improvement of acne vulgaris and sequelae.

关 键 词：chamomilla recutita extract acne marks post-inflammatory erythema post-inflammatory hyperpigmentation 

分 类 号：R28[医药卫生—中药学]