Study on the Synergistic Antioxidant and Anti-Wrinkle Tightening Effect of Vitamin C and Black Ganoderma Extract  

作　　者：Xu Wenfeng Niu Qiang Xu Shanlang Li Shiwei Li Yaxin 

机构地区：[1]Guangdong Youzhi Testing Technology Co.,Ltd.,China

出　　处：《China Detergent & Cosmetics》2025年第1期41-46,共6页日用化学品科学(英文版)

摘　　要：The antioxidant and anti-wrinkle firming effects of a combination of vitamin C(Vc)and black Ganoderma lucidum extract was evaluted.Through the DPPH radical scavenging model and elastase inhibition model,this research investigates the impact of these substances individually and in combination on antioxidant capabilities and anti-wrinkle firming effects.The results demonstrate that the combination of Vc and black Ganoderma lucidum extract exhibits significant antioxidant abilities at various concentrations,and is more effective than when each is used separately,indicating a synergistic interaction between them.Additionally,the combination also shows significant inhibition of elastase,suggesting potential applications in delaying the aging process of the skin.Furthermore,highperformance liquid chromatography(HPLC)was used to determine if reactions occur among the components of the mixture.The findings reveal that the concentration of Vc in the mixture is very close to the theoretical concentration and relatively stable,suggesting that the components function independently.A quantitative analysis using the Bliss independence model further confirms the synergistic effects of Vc and black Ganoderma lucidum extract at specific ratios,providing a scientific basis for the development of efficacious cosmetic products.

关 键 词：Vitamin c black ganoderma lucidum extract ANTIOXIDANT anti-wrinkle firming synergistic effects 

分 类 号：R28[医药卫生—中药学]