Research on PQQ-NA_(2)Ionic Salts to Enhance the Solubility of PQQ-NA_(2)  

作　　者：Fan Lingling Bi Yongxian Zhang Tingzhi 

机构地区：[1]Late-Night Skin Research Laboratory(Shanghai)Co.,Ltd.,China

出　　处：《China Detergent & Cosmetics》2025年第1期47-51,共5页日用化学品科学(英文版)

摘　　要：In order to increase the solubility of pyrroloquinoline quinone disodium salt(PQQ-NA_(2))in water,PQQ-NA_(2)ionic salts formed by PQQ-NA_(2)with amine compounds had been developed.Amine compounds specifically refered to aminomethyl propanol,tromethamine,and matrine.The PQQ-NA_(2)ionic salts solubility test result showed an increase as high as 24-fold compared to dissolving PQQ-NA_(2)alone.The antioxidant test indicated that the ionic salts exhibited significant antioxidant property.Two PQQ-NA_(2)gel formulations were prepared containing the ionic salts,and the stability test and PQQ-NA_(2)content test indicated that the formulations were stable and the loss rate of PQQ was below 10%.

关 键 词：PQQ-NA_(2) SOLUBILITY PQQ-NA_(2)ionic salt PQQ-NA_(2)gel 

分 类 号：TQ658[化学工程—精细化工]