Validation of Anti-Hair Loss Tonic Containing 1.0%Arctium Lappa Root Extract for Chinese Consumers  

作　　者：Zeng Haifeng Lin Xianting Yang Jianzhong Iwano Hideki Sawaki Shigetoyo 

机构地区：[1]Beauty Hi-tech Innovation Co.,Ltd.,Japan [2]Technoble Co.,Ltd.,Japan [3]O and R Co.,Ltd.,Japan

出　　处：《China Detergent & Cosmetics》2025年第1期52-57,共6页日用化学品科学(英文版)

摘　　要：A hair tonic containing 1.0%Arctium lappa root extract(ALRE)was evaluated for its efficacy and tolerability in Chinese consumers.ALRE was selected based on its ability to promote Collagen Type XVII Alpha 1(COL17A1)synthesis,along with other active ingredients targeting scalp health and follicular regeneration.In vitro assays confirmed that ALRE significantly enhanced COL17A1 expression.A 28-day clinical trial involving Chinese participants demonstrated that the tonic reduced hair loss by 37.61%and increased local hair density by 26.63%,with no reported adverse effects.These findings validate the product’s effectiveness in a distinct consumer population and highlight the importance of integrating mechanistic insights with clinical validation.Further research should explore long-term efficacy and demographic-specific responses to optimize its application.

关 键 词：Arctium lappa root extract hair loss hair outer root sheath cells Collagen Type XVII Alpha 1(COL17A1) clinical efficacy Chinese consumers 

分 类 号：TQ658.3[化学工程—精细化工]