奶水牛子宫内膜炎治疗方案对比筛选试验  

Comparative Screening Test of Endometritis Treatment Protocol in Dairy Buffalo

作　　者：梁淦 钟华配 陈笑寒 韦科龙 黄雅鑫 梁宇辰 黄荣春 覃广胜[1] LIANG Gan;ZHONG Huapei;CHEN Xiaohan;WEI Kelong;HUANG Yaxin;LIANG Yuchen;HUANG Rongchun;QIN Guangsheng(Key Laboratory of Buffalo Genetics,Breeding and Reproduction Technology,Guangxi Buffalo Research Institute,Chinese Academy of Agricultural Sciences,Nanning,Guangxi 530001,China)

机构地区：[1]中国农业科学院广西水牛研究所,广西水牛遗传繁育重点实验室,广西南宁530001

出　　处：《中国牛业科学》2025年第1期18-22,共5页China Cattle Science

基　　金：广西重大科技专项(桂科AA22068099-9);广西人才基地项目(桂科AD19259009);广西自然基金项目(2022GXNSFAA035588);国家现代农业产业技术体系广西奶水牛产业创新团队项目(nycytxgxcxtd-2021-21-01);广西农业科技自筹经费项目(Z2022180);广西水牛研究所基本科研业务费(水牛基2201)。

摘　　要：子宫内膜炎是奶水牛产后常见的一种繁殖障碍疾病,严重影响奶水牛养殖场的生产及经济效益,本试验旨在筛选一套简便而有效的奶水牛子宫内膜炎治疗方案。将2021—2022年广西某奶水牛养殖场99头产后患病成年奶水牛随机分为3个组,分别采用盐酸大观霉素和盐酸林可霉素可溶粉溶液(简称A组)、重组溶葡萄球菌酶溶液(简称B组)和宫炎清(简称C组)进行子宫内灌注治疗,对比3组的临床疗效。结果显示,治愈率由高到底依次为A组(75.76%)、B组(67.65%)、C组(53.13%),但差异均不显著(P>0.05);第1疗程有效率B组(44.12%)、A组(42.42%)显著高于C组(18.75%)(P<0.05);第3疗程有效率A组(9.09%)显著低于C组(25.00%)(P<0.05),B组(2.94%)极显著低于C组(P<0.01),但总有效率A(87.88%)、B(82.35%)、C(75.00%)3组间差异不显著(P>0.05)。可见,这3种治疗方案均有助于提高奶水牛子宫内膜炎的治愈率,但各有优劣,其中重组溶葡萄球菌酶的治愈率虽略低于盐酸大观霉素和盐酸林可霉素可溶粉,但见效相对更快,而宫炎清的治愈率和见效时间均稍逊于前两者。Endometritis is a common reproductive disorder in dairy buffalo,which seriously affects the production and economic benefits of dairy buffalo farms.This experiment aims to screen a simple and effective treatment plan for endometritis in dairy buffalo.99 postpartum sick adult dairy buffalo from a dairy buffalo farm in Guangxi from 2021 to 2022 were randomly divided into three groups.The groups were treated with intrauterine infusion therapy using soluble powder solutions of spectinomycin hydrochloride and lincomycin hydrochloride(Group A),recombinant lysostaphylococcus enzyme solution(Group B)and Gongyanqing(Group C),respectively.Compare the clinical curative effect of the 3 groups,the cure rate was group A(75.76%),Group B(67.65%)and Group C(53.13%),but there were no significant differences(P>0.05).The effective rate of the first course of treatment in group B(44.12%)and group A(42.42%)were significantly higher than group C(18.75%)(P<0.05).The third course of treatment group A(9.09%)was significantly lower than Group C(25.00%)(P<0.05),Group B(2.94%)was significantly lower than group C(P<0.01).However,the difference between the total response rate of Group A(87.88%),B(82.35%),and C(75.00%)was not significant(P>0.05).It can be seen that these three different treatment schemes can help to improve the cure rate of endometritis in dairy buffalo,but each has its own advantages and disadvantages.Among them,the recombinant lysostaphine method was relatively faster,followed by spectinomycin hydrochloride and lincomycin hydrochloride soluble powder methods,and the intrauterine perfusion method by Gongyanqing was slightly worse than the former two methods.

关 键 词：奶水牛 子宫内膜炎 抗生素 重组溶葡萄球菌酶 治愈率 

分 类 号：S858.23[农业科学—临床兽医学]