黄连素联合诺氟沙星在老年急性胃肠炎治疗中的评价  

Evaluation of Berberine Combined with Norfloxacin in the Treatment of Acute Gastroenteritis in Elderly Patients

作　　者：屈虹霞 董建毅 Hongxia Qu;Jianyi Dong(Lanzhou University First Hospital(West Station Campus),Lanzhou,Gansu 730050)

机构地区：[1]兰州大学第一医院(西站院区),甘肃兰州730050

出　　处：《医学研究前沿》2025年第1期28-30,共3页Frontiers of Medical Research

摘　　要：目的研究评价黄连素联合诺氟沙星治疗老年急性肠胃炎的临床效果。方法以2022年1月至2023年12月为研究时间,选取收治的80例老年急性肠胃炎患者,所有患者以随机分组程序均分为2组(试验组与参照组),各40例。分别以黄连素联合诺氟沙星、诺氟沙星分别进行治疗。比较两组患者疗效、不良反应发生率、胃肠炎相关症状消失时间及治疗满意度。结果(1)结果显示,试验组患者的疗效明显比参照组更好(100.00%>70.00%),且有效率组间对比有明显差异性(P<0.05=0.001);(2)试验组不良反应发生率明显更低(10.00%<40.00%),且组间对比有明显差异性(P<0.05=0.002);(3)经治疗,试验组患者的腹泻消失时间、腹痛消失时间、呕吐消失时间及发热缓解时间等胃肠炎相关症状消失时间更短,相关指标组间对比差异较大(P<0.05,均为0.001);(4)试验组患者的治疗满意率明显更高(100.00%>70.00%),且治疗满意度组间差异较大(P<0.05=0.001)。结论给予老年急性胃肠炎患者黄连素联合诺氟沙星进行治疗,临床疗效显著,不仅能够显著降低不良反应发生率与提升治疗满意率,还能明显缩短胃肠炎症状消失时间。值得推广。Objective To study and evaluate the clinical efficacy of berberine combined with norfloxacin in the treatment of elderly patients with acute gastroenteritis.Method From January 2022 to December 2023,80 elderly patients with acute gastroenteritis were selected for the study.All patients were randomly divided into two groups(experimental group and reference group),with 40 patients in each group.Treat with berberine combined with norfloxacin and norfloxacin separately.Compare the efficacy,incidence of adverse reactions,disappearance time of gastroenteritis related symptoms,and treatment satisfaction between two groups of patients.Result(1)The results showed that the therapeutic effect of the experimental group was significantly better than that of the reference group(100.00%>70.00%),and there was a significant difference in the effective rate between the groups(P<0.05=0.001);(2)The incidence of adverse reactions in the experimental group was significantly lower(10.00%<40.00%),and there was a significant difference between the groups(P<0.05=0.002);(3)After treatment,the disappearance time of gastroenteritis related symptoms such as diarrhea,abdominal pain,vomiting,and fever relief in the experimental group patients was shorter,and there was a significant difference in related indicators between the groups(P<0.05,all 0.001);(4)The treatment satisfaction rate of patients in the experimental group was significantly higher(100.00%>70.00%),and there was a significant difference in treatment satisfaction between the groups(P<0.05=0.001).Conclusion The combination of berberine and norfloxacin in the treatment of elderly patients with acute gastroenteritis has significant clinical efficacy.It can not only significantly reduce the incidence of adverse reactions and improve treatment satisfaction,but also significantly shorten the time for gastroenteritis symptoms to disappear.Worth promoting.

关 键 词：黄连素 诺氟沙星 老年急性肠胃炎 治疗效果 

分 类 号：R453[医药卫生—治疗学]