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作 者:秦世坤 段明德[1] 梁士杰 张辉[1] 张壮雅[1] QIN Shikun;DUAN Mingde;LIANG Shijie;ZHANG Hui;ZHANG Zhuangya(School of Mechatronics Engineering,Henan University of Science and Technology,Luoyang 471003,China)
出 处:《机械强度》2025年第3期51-59,共9页Journal of Mechanical Strength
基 金:河南省重点科技攻关项目(212102210064);河南省级科技研发计划联合基金项目(222103810030);河南省高等学校重点科研项目(20A460012)。
摘 要:为构建具有良好生物学性能的骨支架结构,基于三周期极小曲面(Triply Periodic Minimal Surface,TPMS)设计不同孔隙率、单胞尺度下的P型、FRD型匀质多孔支架,以及P&FRD梯度多孔支架;并通过试验和有限元仿真的方法,探究单胞类型、孔隙率及单胞尺度对TPMS多孔支架力学和生物学性能的影响。研究结果表明,基于TPMS建立的匀质和梯度多孔支架内部孔道具有良好的连通性;多孔支架的力学性能随着孔隙率的增加而降低,但渗透性则随着孔隙率的增加而提高;增大单胞尺度可以明显提高多孔支架的渗透性;梯度多孔支架的渗透率还受渗流方向的影响;梯度多孔支架能综合各匀质单胞结构的性能特点,在支架不同区域表现出不同的力学和生物学性能,更接近人体骨骼的结构和生物学性能。In order to construct a bone scaffold structure with good biological properties,P-type,FRD-type homogeneous multi-porous scaffolds and P&FRD gradient multi-porous scaffolds with different porosities and unit cell scales were designed based on the triply periodic minimal surface(TPMS).The effects of unit cell types,porosities and unit cell scales on the mechanical and biological properties of TPMS multi-porous scaffolds were investigated by tests and finite element simulation.The results show that the internal pores of homogeneous and gradient multi-porous scaffolds based on TPMS have good connectivity.The mechanical properties of multi-porous scaffolds decrease with the increase of porosity,but the permeability increases with the increase of porosity.Increasing the unit cell scale can significantly improve the permeability of multi-porous scaffolds.The permeability of the gradient multi-porous scaffold is also affected by the seepage direction.The gradient multiporous scaffolds can synthesize the performance characteristics of each homogeneous unit cell structure,and show different mechanical and biological properties in different regions of the scaffold,which is closer to the structure and biological properties of human bone.
分 类 号:TG146.2[一般工业技术—材料科学与工程]
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